Direct Repression of FLIP Expression by c-myc Is a Major Determinant of TRAIL Sensitivity

• Published in: Molecular and Cellular Biology 2004-10, Vol.24 (19), p.8541-8555
• Main Authors: Ricci, M. Stacey, Jin, Zhaoyu, Dews, Michael, Yu, Duonan, Thomas-Tikhonenko, Andrei, Dicker, David T., El-Deiry, Wafik S.
• Format: Article
• Language: English
• Subjects: Animals; Apoptosis - physiology; Apoptosis Regulatory Proteins; Carrier Proteins - biosynthesis; Carrier Proteins - genetics; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Growth and Development; Gene Expression Regulation - physiology; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins - metabolism; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc - metabolism; RNA Interference; RNA, Messenger - metabolism; TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic - physiology; Tumor Necrosis Factor-alpha - metabolism
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.24.19.8541-8555.2004

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