Reference values for TSH may be inadequate to define hypothyroidism in persons with morbid obesity: [e-mail] study

• Published in: Obesity (Silver Spring, Md.) Md.), 2017-04, Vol.25 (4), p.788-793
• Main Authors: Valdés, Sergio, Maldonado‐Araque, Cristina, Lago‐Sampedro, Ana, Lillo‐Muñoz, Juan Antonio, Garcia‐Fuentes, Eduardo, Perez‐Valero, Vidal, Gutiérrez‐Repiso, Carolina, Garcia‐Escobar, Eva, Goday, Albert, Urrutia, Inés, Peláez, Laura, Calle‐Pascual, Alfonso, Bordiú, Elena, Castaño, Luis, Castell, Conxa, Delgado, Elias, Menéndez, Edelmiro, Franch‐Nadal, Josep, Gaztambide, Sonia, Girbés, Joan, Ortega, Emilio, Vendrell, Joan, Chacón, Matilde R., Javier Chaves, F., Soriguer, Federico, Rojo‐Martínez, Gemma
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Adults; Aged; Aged, 80 and over; Autoantibodies - blood; Cross-Sectional Studies; Family medical history; Female; Gastrointestinal surgery; Humans; Hypothyroidism; Hypothyroidism - blood; Hypothyroidism - diagnosis; Iodine; Laboratories; Male; Mens health; Metabolism; Methods; Middle Aged; Obesity; Obesity, Morbid - blood; Obesity, Morbid - complications; Observer Variation; Overweight - blood; Overweight - complications; Population; Prevalence; Questionnaires; Reference Values; Spain; Thinness - blood; Thinness - complications; Thyroid diseases; Thyroid Function Tests; Thyrotropin - blood; Thyroxine - blood; Triiodothyronine - blood; Weight control; Young Adult
• ISSN: 1930-7381; 1930-739X
• DOI: 10.1002/oby.21796

Objective To analyze the reference range of thyroid‐stimulating hormone (TSH) in different BMI categories and its impact on the classification of hypothyroidism. Methods The study included 3,928 individuals free of thyroid disease (without previous thyroid disease, no interfering medications, TSH