New naphthalene derivative from the leaves of Cassia grandis L

Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2), afzelin (3), quercitrin (4), epic...

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Bibliographic Details
Published in:Natural product research 2017-08, Vol.31 (15), p.1733-1738
Main Authors: Trinh, Pham Thi Nhat, Luan, Ngoc Quoc, Tri, Mai Dinh, Khanh, Vu Duy, An, Nguyen Huu, Minh, Phan Nhat, An, Pham Ngoc, Thuy, Nguyen Thi Le, Phung, Nguyen Kim Phi, Dung, Le Tien
Format: Article
Language:English
Subjects:
Aloe
Anthraquinones - chemistry
Anthraquinones - isolation & purification
Back pain
Cassgranon D
Cassia - chemistry
Cassia - metabolism
Cassia grandis
Disorders
Emodin
Epicatechin
Ethyl acetate
Infrared spectroscopy
Leaves
Magnetic Resonance Spectroscopy
Mannosides - chemistry
Mannosides - isolation & purification
Methanol
Methanol - chemistry
Molecular Structure
Naphthalene
naphthalene derivative
Naphthalenes - chemistry
NMR
Nuclear magnetic resonance
Pain
Plant Extracts - chemistry
Plant Leaves - chemistry
Plants, Medicinal - chemistry
Proanthocyanidins - chemistry
Proanthocyanidins - isolation & purification
Quercetin - analogs & derivatives
Quercetin - chemistry
Quercetin - isolation & purification
Rutin
Rutin - analysis
Secondary Metabolism
Skin
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Summary:Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2), afzelin (3), quercitrin (4), epicatechin (5), (-)-epiafzelechin (6), isoquercitrin (7) and aloe emodin (8) were isolated from the ethyl acetate and methanol extracts. Their structures were elucidated by spectral evidences (UV, IR, MS, 1 H, 13 C, DEPT, HSQC and HMBC NMR), as well as by comparing with published data.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2017.1290615