Left ventricular mechanics in isolated mild mitral stenosis: a three dimensional speckle tracking study

• Published in: The International Journal of Cardiovascular Imaging 2017-09, Vol.33 (9), p.1323-1330
• Main Authors: Poyraz, Esra, Öz, Tuğba Kemaloğlu, Zeren, Gönül, Güvenç, Tolga Sinan, Dönmez, Cevdet, Can, Fatma, Güvenç, Rengin Çetin, Dayı, Şennur Ünal
• Format: Article
• Language: English
• Subjects: Adult; Asymptomatic Diseases; Beta blockers; Biomechanical Phenomena; Cardiac arrhythmia; Cardiac Imaging; Cardiology; Case-Control Studies; Contractility; Correlation analysis; Data analysis; Data processing; Dimensional measurement; Echocardiography; Echocardiography, Doppler - methods; Echocardiography, Three-Dimensional - methods; Female; Heart; Humans; Image Interpretation, Computer-Assisted; Imaging; Male; Mechanics (physics); Medicine; Medicine & Public Health; Middle Aged; Mitral valve; Mitral Valve Stenosis - complications; Mitral Valve Stenosis - diagnostic imaging; Mitral Valve Stenosis - physiopathology; Myocardial Contraction; Original Paper; Patients; Predictive Value of Tests; Prospective Studies; Radiology; Rheumatic Heart Disease - complications; Rheumatic Heart Disease - diagnostic imaging; Rheumatic Heart Disease - physiopathology; Risk Factors; Severity of Illness Index; Stenosis; Stroke Volume; Torsion; Tracking; Ventricle; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - etiology; Ventricular Dysfunction, Left - physiopathology; Ventricular Function, Left
• ISSN: 1569-5794; 1573-0743; 1875-8312
• DOI: 10.1007/s10554-017-1109-z

In a fraction of patients with mild mitral stenosis, left ventricular systolic function deteriorates despite the lack of hemodynamic load imposed by the dysfunctioning valve. Neither the predisposing factors nor the earlier changes in left ventricular contractility were understood adequately. In the present study we aimed to evaluate left ventricular mechanics using three-dimensional (3D) speckle tracking echocardiography. A total of 31 patients with mild rheumatic mitral stenosis and 27 healthy controls were enrolled to the study. All subjects included to the study underwent echocardiographic examination to collect data for two- and three-dimensional speckle-tracking based stain, twist angle and torsion measurements. Data was analyzed offline with a echocardiographic data analysis software. Patients with rheumatic mild MS had lower global longitudinal (p