Fertility concerns among breast cancer patients in Mexico

• Published in: Breast (Edinburgh) 2017-06, Vol.33, p.71-75
• Main Authors: Villarreal-Garza, Cynthia, Martinez-Cannon, Bertha Alejandra, Platas, Alejandra, Mohar, Alejandro, Partridge, Ann H, Gil-Moran, Arnoldo, Fonseca, Alan, Vega, Yoatzin, Bargallo-Rocha, Enrique, Cardona-Huerta, Servando, Lopez-Aguirre, Yadira Estefany, Barragan-Carrillo, Regina, Castro-Sanchez, Andrea
• Format: Article
• Language: English
• Subjects: Adult; Antineoplastic Agents - adverse effects; Breast neoplasm; Breast Neoplasms - drug therapy; Breast Neoplasms - psychology; Cross-Sectional Studies; Female; Fertility preservation; Fertility Preservation - psychology; Hematology, Oncology and Palliative Medicine; Humans; Infertility, Female - chemically induced; Infertility, Female - psychology; Mexico; Quality of life; Surveys and Questionnaires; Young Adult; Young women
• ISSN: 0960-9776; 1532-3080
• DOI: 10.1016/j.breast.2017.02.010

Abstract Objective Young women represent a high proportion of the total number of breast cancer (BC) patients in Mexico; however, no previous studies addressing their attitudes regarding the risk of chemotherapy-induced infertility and its contributing factors are available. The aim of this study was to evaluate the concerns of young women with BC towards the risk of infertility in two referral centers in Mexico with access to public health services. Methods A cross-sectional study including women with newly or previously detected BC aged 40 years or younger at diagnosis was conducted. Variables regarding concerns about fertility were collected from an adapted version of the Fertility Issues Survey. Results 134 consecutive eligible women responded to the in-person paper survey. 55% were partnered, 35.1% had no children, and 48% reported willingness to have children prior to BC diagnosis. Only 3% of patients considered to be able to afford extra expenses. At diagnosis, 44% of women expressed some level of concern about infertility risk. The only factor significantly associated with fertility concern was the desire of having children prior to diagnosis (OR 11.83, p = 0.006). Only 30.6% patients recalled having received information regarding infertility risk from their physicians. Conclusion A minority of young women with breast cancer in Mexico is informed about the risk of BC treatment-induced infertility, despite substantial interest. Informing all patients about infertility risk and available options for fertility preservation should be an essential aspect of the supportive care of young women with BC, even in low-middle income countries such as Mexico.