Effects of aspirin on small-cell lung cancer mortality and metastatic presentation

Highlights • Aspirin has been shown to reduce cancer incidence and mortality, including lung cancer. • Data on the effects of aspirin on small-cell lung cancer (SCLC) are sparse, and conflicting. • We have shown in multivariate analysis of a large cohort of patients with SCLC that aspirin does not i...

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Bibliographic Details
Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2017-04, Vol.106, p.67-69
Main Author: Maddison, Paul
Format: Article
Language:English
Subjects:
Aged
Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Anti-Inflammatory Agents, Non-Steroidal - pharmacology
Aspirin
Aspirin - administration & dosage
Aspirin - pharmacology
Aspirin - therapeutic use
Cyclooxygenase 2 - metabolism
Female
Hematology, Oncology and Palliative Medicine
Humans
Lung Neoplasms - diagnosis
Lung Neoplasms - drug therapy
Lung Neoplasms - mortality
Male
Middle Aged
Neoplasm Metastasis - drug therapy
Neoplasm Metastasis - pathology
Neoplasm Staging
Observational
Prospective
Prospective Studies
Pulmonary/Respiratory
Small Cell Lung Carcinoma - diagnosis
Small Cell Lung Carcinoma - drug therapy
Small Cell Lung Carcinoma - mortality
Small-cell lung cancer
Survival
Survival Analysis
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Summary:Highlights • Aspirin has been shown to reduce cancer incidence and mortality, including lung cancer. • Data on the effects of aspirin on small-cell lung cancer (SCLC) are sparse, and conflicting. • We have shown in multivariate analysis of a large cohort of patients with SCLC that aspirin does not improve cancer survival.
ISSN:0169-5002
1872-8332
DOI:10.1016/j.lungcan.2017.01.018