Criteria sets for primary Sjogren’s syndrome are not adequate for those presenting with extraglandular organ involvements as their dominant clinical features

Patients with primary Sjogren’s syndrome (pSS) may go undiagnosed or be misclassified due to the insidious nature and wide spectrum of the disease. The available several classification criteria emphasize glandular findings. We aimed to analyze the efficiency of various classification criteria sets i...

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Bibliographic Details
Published in:Rheumatology international 2017-05, Vol.37 (5), p.675-684
Main Authors: Kabasakal, Yasemin, Kitapçıoğlu, Gul, Karabulut, Gonca, Tezcan, Mehmet, Balkarlı, Ayse, Aksoy, Adem, Yavuz, Şule, Yılmaz, Sema, Kaşifoğlu, Timuçin, Kalyoncu, Umut, Dalkılıç, Ediz, Tufan, Abdurrahman, Mercan, Rıdvan, Yıldız, Fatih, Şentürk, Taşkın, Önen, Fatoş, Bes, Cemal, Erken, Eren, Tunç, Ercan, Kamalı, Sevil, Tarhan, Emine, Yazıcı, Ayten, Düzgün, Nurşen, Bıçakçıgil, Müge, Yılmaz, Sedat, Özmen, Mustafa, Öcal, Lale, Alibaz-Öner, Fatma, Solmaz, Dilek, Çobankara, Veli, Nalbant, Selim, Kasapoğlu Günal, Esen, Kaşkari, Derya, Göker, Berna
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Female
Food for Thought
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Rheumatology
Sjogren's Syndrome - diagnosis
Symptom Assessment
Young Adult
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Summary:Patients with primary Sjogren’s syndrome (pSS) may go undiagnosed or be misclassified due to the insidious nature and wide spectrum of the disease. The available several classification criteria emphasize glandular findings. We aimed to analyze the efficiency of various classification criteria sets in patients diagnosed on the clinical basis by expert opinion and to compare those pSS patients who fulfilled these criteria with those who did not. This is a multicenter study in which 834 patients from 22 university-based rheumatology clinics are included. Diagnosis of pSS was made on the clinical basis by the expert opinion. In this study, we only interviewed patients once and collected available data from the medical records. The European criteria, American-European Consensus Group (AECG) and American College of Rheumatology (ACR) Sjogren’s criteria were applied. Majority of the patients were women (F/M was 20/1). The median duration from the first pSS-related symptom to diagnosis was significantly shorter in men (2.5 ± 2.3 vs 4.3 ± 5.9 years) ( p  = 0 
ISSN:0172-8172
1437-160X
DOI:10.1007/s00296-017-3691-8