Sensitization to bovine serum albumin as a possible cause of allergic reactions to vaccines

Highlights • Allergy to beef and pork is relatively common in Sri Lanka. • Patients with immediate hypersensitivity are allergic to cow’s milk or beef/pork. • IgE to gelatin was not seen in our cohort. • The majority had specific IgE to bovine serum albumin not described previously. • Patients with...

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Bibliographic Details
Published in:Vaccine 2017-03, Vol.35 (11), p.1494-1500
Main Authors: de Silva, Rajiva, Dasanayake, W.M.D.K, Wickramasinhe, G.D, Karunatilake, Chandima, Weerasinghe, Nayani, Gunasekera, Peshala, Malavige, Gathsaurie Neelika
Format: Article
Language:English
Subjects:
Adolescent
Allergens - administration & dosage
Allergens - immunology
Allergies
Allergy and Immunology
Anaphylaxis
Animals
Bovine serum albumin
Casein
Cattle
Child
Child, Preschool
Diphtheria
Excipients
Female
Food allergies
Gelatin
Humans
Hypersensitivity
Immunization
Infant
Male
Measles
Milk
MMR
Mumps
Patients
Proteins
Rubella
Serum Albumin, Bovine - administration & dosage
Serum Albumin, Bovine - immunology
Sri Lanka
Tetanus
Vaccine
Vaccines
Vaccines - administration & dosage
Vaccines - adverse effects
Whooping cough
Yogurt
Young Adult
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Summary:Highlights • Allergy to beef and pork is relatively common in Sri Lanka. • Patients with immediate hypersensitivity are allergic to cow’s milk or beef/pork. • IgE to gelatin was not seen in our cohort. • The majority had specific IgE to bovine serum albumin not described previously. • Patients with CMA and vaccine allergy had significantly higher Casein specific IgE.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2017.02.009