Cerclage for sonographic short cervix in singleton gestations without prior spontaneous preterm birth: systematic review and meta‐analysis of randomized controlled trials using individual patient‐level data

ABSTRACT Objective The aim of this systematic review and meta‐analysis was to quantify the efficacy of cervical cerclage in preventing preterm birth (PTB) in asymptomatic singleton pregnancies with a short mid‐trimester cervical length (CL) on transvaginal sonography (TVS) and without prior spontane...

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Bibliographic Details
Published in:Ultrasound in obstetrics & gynecology 2017-11, Vol.50 (5), p.569-577
Main Authors: Berghella, V., Ciardulli, A., Rust, O. A., To, M., Otsuki, K., Althuisius, S., Nicolaides, K. H., Roman, A., Saccone, G.
Format: Article
Language:English
Subjects:
Antibiotics
Birth
Cerclage, Cervical - statistics & numerical data
cervical length
Cervical Length Measurement - methods
Cervix
Clinical trials
Combined Modality Therapy
Evidence-based medicine
Female
Fetal Membranes, Premature Rupture - etiology
Fetal Membranes, Premature Rupture - prevention & control
Gestational Age
Humans
intensive care
Membranes
Meta-analysis
Neonates
Pregnancy
Pregnancy Trimester, Second
Premature birth
Premature Birth - etiology
Premature Birth - prevention & control
prematurity
preterm birth
Quality
Randomization
Randomized Controlled Trials as Topic
Reviews
Statistical analysis
Subgroups
Sutures
Systematic review
Therapy
Tocolytic Agents - administration & dosage
Translations
transvaginal ultrasound
Treatment Outcome
ultrasound‐indicated cerclage
Uterine Diseases - complications
Uterine Diseases - therapy
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Summary:ABSTRACT Objective The aim of this systematic review and meta‐analysis was to quantify the efficacy of cervical cerclage in preventing preterm birth (PTB) in asymptomatic singleton pregnancies with a short mid‐trimester cervical length (CL) on transvaginal sonography (TVS) and without prior spontaneous PTB. Methods Electronic databases were searched from inception of each database until February 2017. No language restrictions were applied. All randomized controlled trials (RCTs) of asymptomatic singleton pregnancies without prior spontaneous PTB, found to have short CL
ISSN:0960-7692
1469-0705
DOI:10.1002/uog.17457