Immunohistochemical Staining of Pediatric Solitary Angiokeratomas

The precise etiology and subtype of vessels constituting angiokeratomas is poorly understood. We sought to characterize the vessels by studying prospero‐related homeobox gene‐1 and D2‐40 expression in 22 pediatric solitary angiokeratomas. Routine histologic examination demonstrated a mix of lymph‐co...

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Bibliographic Details
Published in:Pediatric dermatology 2017-03, Vol.34 (2), p.211-213
Main Authors: Prindaville, Brea, Lawrence, Hillary, Singh, Vivekanand, Nopper, Amy J., Horii, Kimberly A.
Format: Article
Language:English
Subjects:
Adolescent
Angiokeratoma - pathology
Child
Child, Preschool
Etiology
Female
Homeobox
Humans
Infant
Lymph
Male
Pediatrics
Prospero protein
Retrospective Studies
Skin Neoplasms - pathology
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Summary:The precise etiology and subtype of vessels constituting angiokeratomas is poorly understood. We sought to characterize the vessels by studying prospero‐related homeobox gene‐1 and D2‐40 expression in 22 pediatric solitary angiokeratomas. Routine histologic examination demonstrated a mix of lymph‐containing vessels and erythrocyte‐filled small vessels. Our results suggest that angiokeratomas may in part be comprised of vessels with lymphatic differentiation.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.13089