Ascending aortic distensibility and target organ damage in primary hypertension without diabetes

• Published in: The International Journal of Cardiovascular Imaging 2017-08, Vol.33 (8), p.1245-1251
• Main Authors: Jia, Chong-fu, Wang, Zhao-qian, Sun, Xi-xia, Yang, Zhi-qiang, Zou, Yu-jie, Jiang, Yi-nong
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Ankle; Ankle Brachial Index; Aorta; Aorta - diagnostic imaging; Aorta - physiopathology; Aortography - methods; Blood Pressure; Cardiac Imaging; Cardiology; Chi-Square Distribution; Computed Tomography Angiography; Contrast media; Coronary Angiography - methods; Diabetes mellitus; EKG; Female; Health risk assessment; Humans; Hypertension; Hypertension - complications; Hypertension - diagnostic imaging; Hypertension - physiopathology; Image reconstruction; Imaging; Logistic Models; Male; Medicine; Medicine & Public Health; Middle Aged; Multidetector Computed Tomography; Multivariate Analysis; Original Paper; Prognosis; Pulse Wave Analysis; Radiation; Radiation dosage; Radiology; Regression analysis; Risk Factors; Scanning; Vascular Stiffness; Velocity; Wave velocity
• ISSN: 1569-5794; 1573-0743; 1875-8312
• DOI: 10.1007/s10554-017-1099-x

To investigate the relationship between ascending aortic distensibility (AAD) and hypertensive target organ damage (TOD) and its potential value in prediction. One hundred and sixty seven primary hypertension inpatients who underwent coronary CTA examination were enrolled into our study. Retrospective ECG-triggering scanning mode were applied and the images were reconstructed every 5% phase in the entire R–R interval. Maximum and minimum ascending aortic areas as well as the AAD value were calculated on the interested slice. AAD (P