Effect of 5-aminolevulinic acid photodynamic therapy on keratinocyte proliferation and apoptosis in condyloma acuminatum

Highlights • 5-Aminolevulinic acid photodynamic therapy of condyloma acuminatum was evaluated. • Condyloma acuminatum tissue samples were taken before and after therapy. • The effects of therapy on keratinocyte proliferation and apoptosis were evaluated. • The therapy inhibited proliferation and ind...

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Bibliographic Details
Published in:Photodiagnosis and photodynamic therapy 2017-06, Vol.18, p.310-314
Main Authors: Yin, Guangwen, Sha, Ke, Cai, Bingjie, Li, Fangfang, Li, Xuyang, Xia, Xianxian, Pan, Xinxin
Format: Article
Language:English
Subjects:
5-aminolevulinic acid photodynamic therapy
Adolescent
Adult
Aminolevulinic Acid - administration & dosage
Apoptosis
Apoptosis - drug effects
Apoptosis - radiation effects
Cell Proliferation - drug effects
Cell Proliferation - radiation effects
Condyloma acuminatum
Condylomata Acuminata - drug therapy
Condylomata Acuminata - pathology
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
Hematology, Oncology and Palliative Medicine
Humans
Internal Medicine
Keratinocytes - drug effects
Keratinocytes - pathology
Keratinocytes - radiation effects
Ki-67
Middle Aged
Photochemotherapy - methods
Photosensitizing Agents - administration & dosage
Proliferation
Treatment Outcome
Young Adult
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Summary:Highlights • 5-Aminolevulinic acid photodynamic therapy of condyloma acuminatum was evaluated. • Condyloma acuminatum tissue samples were taken before and after therapy. • The effects of therapy on keratinocyte proliferation and apoptosis were evaluated. • The therapy inhibited proliferation and induced apoptosis in keratinocytes.
ISSN:1572-1000
1873-1597
DOI:10.1016/j.pdpdt.2017.03.003