Exploring the bioprospecting and biotechnological potential of white-rot and anaerobic Neocallimastigomycota fungi: peptidases, esterases, and lignocellulolytic enzymes

• Published in: Applied microbiology and biotechnology 2017-04, Vol.101 (8), p.3089-3101
• Main Authors: da Silva, Ronivaldo Rodrigues, Pedezzi, Rafael, Souto, Tatiane Beltramini
• Format: Article
• Language: English
• Subjects: Anaerobiosis; Biochemistry; Biodegradable materials; Biofuels; Biogas; Biological products; Biomass; Biomass energy; Biomedical and Life Sciences; Bioprospecting - methods; Biotechnology; Biotechnology - methods; Biotechnology - trends; Cellulose; Chemical compounds; Enzymes; Esterases - metabolism; Feeds; Fungi; Herbivores; Life Sciences; Lignin; Lignin - metabolism; Lignocellulose; Metabolism; Metabolites; Microbial Genetics and Genomics; Microbiology; Mini-Review; Natural resources; Neocallimastigomycota - enzymology; Neocallimastigomycota - metabolism; Peptide Hydrolases - metabolism; Polymers; Polymers - metabolism; Proteases; Soil Microbiology; Studies; Wood; Wood - microbiology; Yeast
• ISSN: 0175-7598; 1432-0614
• DOI: 10.1007/s00253-017-8225-5

Fungi constitute an invaluable natural resource for scientific research, owing to their diversity; they offer a promising alternative for bioprospecting, thus contributing to biotechnological advances. For a long time, extensive information has been exploited and fungal products have been tested as a source of natural compounds. In this context, enzyme production remains a field of interest, since it offers an efficient alternative to the hazardous processes of chemical transformations. Owing to their vast biodiversity and peculiar biochemical characteristics, two fungal categories, white-rot and anaerobic Neocallimastigomycota , have gathered considerable attention for biotechnological applications. These fungi are known for their ability to depolymerize complex molecular structures and are used in degradation of lignocellulosic biomass, improvement of animal feed digestibility, biogas and bioethanol production, and various other applications. However, there are only limited reports that describe proteolytic enzymes and esterases in these fungi and their synergistic action with lignocellulolytic enzymes on degradation of complex polymers. Thus, in this minireview, we focus on the importance of these organisms in enzyme technology, their bioprospecting, possibility of integration of their enzyme repertoire, and their prospects for future biotechnological innovation.