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The levonorgestrel-releasing intrauterine device potentiates stress reactivity
Highlights • LNG-IUD is associated with a robust potentiation of HPA axis responsivity. • LNG-IUD potentiates the autonomic heart rate response during psychosocial stress. • The mechanism of LNG-IUD sensitization of the HPA axis is centrally-mediated
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Published in: | Psychoneuroendocrinology 2017-06, Vol.80, p.39-45 |
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container_title | Psychoneuroendocrinology |
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creator | Aleknaviciute, Jurate Tulen, Joke H.M De Rijke, Yolanda B Bouwkamp, Christian G van der Kroeg, Mark Timmermans, Mirjam Wester, Vincent L Bergink, Veerle Hoogendijk, Witte J.G Tiemeier, Henning van Rossum, Elisabeth F.C Kooiman, Cornelis G Kushner, Steven A |
description | Highlights • LNG-IUD is associated with a robust potentiation of HPA axis responsivity. • LNG-IUD potentiates the autonomic heart rate response during psychosocial stress. • The mechanism of LNG-IUD sensitization of the HPA axis is centrally-mediated |
doi_str_mv | 10.1016/j.psyneuen.2017.02.025 |
format | article |
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subjects | Adrenocorticotropic hormone Adrenocorticotropic Hormone - metabolism Adult Affective disorders Autonomic nervous system Contraceptive Agents, Female - pharmacology Cortisol Cross-Sectional Studies Endocrinology & Metabolism Ethinyl Estradiol Female Humans Hydrocortisone - analysis Hydrocortisone - blood Hypothalamo-Hypophyseal System - drug effects Hypothalamus-Pituitary-Adrenal (HPA) axis Intrauterine Devices Levonorgestrel - metabolism Levonorgestrel - pharmacology Levonorgestrel-releasing intrauterine device Long-acting reversible contraception (LARC) Pituitary-Adrenal System - drug effects Psychiatry Saliva Young Adult |
title | The levonorgestrel-releasing intrauterine device potentiates stress reactivity |
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