In Vitro Evaluation of Colloidal Silver on Immune Function: Antilymphoproliferative Activity

Colloidal silver (AgC) is currently used by humans and it can be internalized through inhalation, injection, ingestion, and dermal contact. However, there is limited information about immunological activity; more investigations using colloidal silver are needed. In the present study, the effects of...

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Bibliographic Details
Published in:Journal of nanomaterials 2016-01, Vol.2016 (2016), p.1-8
Main Authors: Rodriguez-Padilla, Cristina, Tamez-Guerra, Reyes Silvestre, Rodríguez-Salazar, María del Carmen, Resendez-Pérez, D., Alcocer González, Juan Manuel, Coronado-Cerda, Erika Evangelina, Zarate-Triviño, D. G., Mendoza-Gamboa, Edgar, Franco-Molina, Moisés Armides, Rivera-Morales, Lydia Guadalupe
Format: Article
Language:English
Subjects:
Apoptosis
Aqueous solutions
Cancer
Cell cycle
Cell growth
Colloids
Concanavalin A
Cytokines
Cytotoxicity
Dehydrogenases
Immune system
Immune systems
Immunology
Ingestion
Laboratories
Leukemia
Lymphoma
Nanomaterials
Nanoparticles
Phagocytosis
Silver
Studies
Toxicity
Virology
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Summary:Colloidal silver (AgC) is currently used by humans and it can be internalized through inhalation, injection, ingestion, and dermal contact. However, there is limited information about immunological activity; more investigations using colloidal silver are needed. In the present study, the effects of AgC (17.5 ng/mL) on immunological parameters (proliferation and immunophenotyping) using human peripheral blood mononuclear cells (PBMC) and macrophages (phagocytosis) and cytotoxicity on leukemia and lymphoma cancer cell lines (1.75 to 17.5 ng/mL) were investigated. AgC was observed to significantly (p
ISSN:1687-4110
1687-4129
DOI:10.1155/2016/4176212