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Imaging performance in guiding response to neoadjuvant therapy according to breast cancer subtypes: A systematic literature review

Highlights • 15 observational studies examined imaging performance for measuring response during NAC. • Evidence to conclude on the preferred imaging technique per BC subtype is lacking. •18 FDG-PET/CT seems to be preferred in ER-negative/HER2positive BC over MRI. • MRI and18 FDG-PET/CT are promisin...

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Bibliographic Details
Published in:Critical reviews in oncology/hematology 2017-04, Vol.112, p.198-207
Main Authors: Lindenberg, Melanie A, Miquel-Cases, Anna, Retèl, Valesca P, Sonke, Gabe S, Wesseling, Jelle, Stokkel, Marcel P.M, van Harten, Wim H
Format: Article
Language:English
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Summary:Highlights • 15 observational studies examined imaging performance for measuring response during NAC. • Evidence to conclude on the preferred imaging technique per BC subtype is lacking. •18 FDG-PET/CT seems to be preferred in ER-negative/HER2positive BC over MRI. • MRI and18 FDG-PET/CT are promising in both triple negative and HER2-positive BC. • Consensus should be reached on: interval time, cut-off values, and pCR definitions.
ISSN:1040-8428
1879-0461
DOI:10.1016/j.critrevonc.2017.02.014