Aquagenic wrinkling of the palms: a case report and literature review

Aquagenic wrinkling of the palms (AWP) is an unusual and rare dermatological condition characterized by excessive palmar wrinkling, occurring within a few minutes of water exposure. Cystic fibrosis (CF) or CF carrier state associated forms, drug induced cases, and idiopathic forms have been describe...

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Bibliographic Details
Published in:Dermatology online journal 2016-09, Vol.22 (9)
Main Authors: Megna, Matteo, Cantelli, Mariateresa, Martellotta, Donata, Calabrò, Gabriella, Balato, Anna, Ayala, Fabio
Format: Article
Language:English
Subjects:
Adult
Female
Hand Dermatoses - diagnosis
Hand Dermatoses - etiology
Humans
Water
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Summary:Aquagenic wrinkling of the palms (AWP) is an unusual and rare dermatological condition characterized by excessive palmar wrinkling, occurring within a few minutes of water exposure. Cystic fibrosis (CF) or CF carrier state associated forms, drug induced cases, and idiopathic forms have been described. We report the case of a 27-year-old woman with a 7-year history of transient excessive wrinkling of her palms after brief exposure to water. We present also a comprehensive review of the literature. We believe that AWP has been underdiagnosed thus far and we would like to encourage investigations such as sweat chloride test or genetic studies in these patients because of the association with CF or CF carrier state, particularly when AWP appears in younger ages.
ISSN:1087-2108
1087-2108
DOI:10.5070/D3229032504