The natural history of cystic echinococcosis in untreated and albendazole-treated patients

This study provides statistical confirmation that the WHO ultrasound classification of CE reflects the natural history of CE in untreated and albendazole-treated patients. [Display omitted] The World Health Organization (WHO) treatment protocols for cystic echinococcosis (CE) are based on the standa...

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Bibliographic Details
Published in:Acta tropica 2017-07, Vol.171, p.52-57
Main Authors: Solomon, N., Kachani, M., Zeyhle, E., Macpherson, C.N.L.
Format: Article
Language:English
Subjects:
Adult
Albendazole
Albendazole - therapeutic use
Anthelmintics - therapeutic use
Classification
Cystic echinococcosis
Echinococcosis - classification
Echinococcosis - diagnostic imaging
Echinococcosis - drug therapy
Echinococcosis - epidemiology
Female
Humans
Kenya - epidemiology
Male
Mass Screening
Medical Records
Middle Aged
Morocco - epidemiology
Natural history
Parasitology
Ultrasonography
Ultrasound
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Summary:This study provides statistical confirmation that the WHO ultrasound classification of CE reflects the natural history of CE in untreated and albendazole-treated patients. [Display omitted] The World Health Organization (WHO) treatment protocols for cystic echinococcosis (CE) are based on the standardized ultrasound (US) classification. This study examined whether the classification reflected the natural history of CE in untreated and albendazole-treated patients. Data were collected during mass US screenings in CE endemic regions among transhumant populations, the Turkana and Berber peoples of Kenya and Morocco. Cysts were classified using the WHO classification. Patient records occurring prior to treatment, and after albendazole administration, were selected. 852 paired before/after observations of 360 cysts from 257 patients were analyzed. A McNemar-Bowker χ2 test for symmetry was significant (p
ISSN:0001-706X
1873-6254
DOI:10.1016/j.actatropica.2017.03.018