Prognostic analysis for short - and long-term outcomes of newly diagnosed epilepsy

Highlights • Time interval between index seizure and AED start is associated with short term outcome, while it doesn’t influence long term outcome. • The number of seizures ≥ 2 in the first year after AED start is the independent risk factor for both short and long term outcome. • No significant dif...

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Bibliographic Details
Published in:Seizure (London, England) England), 2017-04, Vol.47, p.92-98
Main Authors: Jiang, Yong-li, MD, Yuan, Fang, MD, Yang, Fang, MD, PhD, Sun, Xiao-long, MD, Yang, Xi-ai, MD, Song, Lu, MD, Jiang, Wen, MD, PhD
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Anticonvulsants - therapeutic use
Child
Child, Preschool
Cohort study
Epilepsy - diagnosis
Epilepsy - drug therapy
Epilepsy - epidemiology
Female
Follow-Up Studies
Humans
Infant
Male
Middle Aged
Neurology
Newly diagnosed epilepsy
Prognosis
Retention rates
Retrospective Studies
Risk Factors
Seizure frequency
Time Factors
Treatment Outcome
Young Adult
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Summary:Highlights • Time interval between index seizure and AED start is associated with short term outcome, while it doesn’t influence long term outcome. • The number of seizures ≥ 2 in the first year after AED start is the independent risk factor for both short and long term outcome. • No significant difference of retention rate was found between the traditional and new AEDs in patients who attained terminal remission.
ISSN:1059-1311
1532-2688
DOI:10.1016/j.seizure.2017.02.018