Loading…
Association of objectively measured physical activity with established and novel cardiovascular biomarkers in elderly subjects: every step counts
Objective To analyse the relationship between objectively measured daily walking duration and cardiovascular biomarkers of inflammation, cardiac dysfunction and renal impairment. Methods Between March 2009 and April 2010, physical activity was assessed in 1253 community-dwelling individuals living i...
Saved in:
| Published in: | Journal of epidemiology and community health (1979) 2013-02, Vol.67 (2), p.194-197 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-b486t-8ba9b57fa0c6f1de272e43d7b3bef91a2ee30547a439909add71bcda308c908e3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-b486t-8ba9b57fa0c6f1de272e43d7b3bef91a2ee30547a439909add71bcda308c908e3 |
| container_end_page | 197 |
| container_issue | 2 |
| container_start_page | 194 |
| container_title | Journal of epidemiology and community health (1979) |
| container_volume | 67 |
| creator | Klenk, Jochen Denkinger, Michael Nikolaus, Thorsten Peter, Richard Rothenbacher, Dietrich Koenig, Wolfgang |
| description | Objective To analyse the relationship between objectively measured daily walking duration and cardiovascular biomarkers of inflammation, cardiac dysfunction and renal impairment. Methods Between March 2009 and April 2010, physical activity was assessed in 1253 community-dwelling individuals living in Germany aged ≥65 years (57% men) over 1 week using a thigh-worn accelerometer. C reactive protein (CRP), white blood cells (WBC), N-terminal pro-brain natriuretic peptide, high-sensitive troponin T (hsTnT), creatinine (Cr) and cystatin C (CysC) were also measured. Least-square means of daily walking duration were calculated for quartiles of each biomarker adjusted for sex, age, pre-existing cardiovascular disease and smoking status. Results After adjustment for covariates, statistically significant linear associations with walking duration were observed for WBC, hsTnT, Cr and CysC. CRP quartiles 1 and 2 showed no significant difference followed by a significant inverse dose–response relationship. A similar pattern, but less pronounced, was seen for N-terminal pro-brain natriuretic peptide. Mean differences between the first two quartiles of CRP and its fourth quartile were 17 min. Between categories 1 (more beneficial) and 4 of WBC, hsTnT, Cr and CysC the differences were 15, 12, 23 and 20 min, respectively. Conclusion Increased walking duration is associated with a more favourable profile of cardiovascular biomarkers in elderly subjects. |
| doi_str_mv | 10.1136/jech-2012-201312 |
| format | article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1881751521</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>43281495</jstor_id><sourcerecordid>43281495</sourcerecordid><originalsourceid>FETCH-LOGICAL-b486t-8ba9b57fa0c6f1de272e43d7b3bef91a2ee30547a439909add71bcda308c908e3</originalsourceid><addsrcrecordid>eNqFkduL1DAUxoso7rj67osSEEGQai5tk_i2DN5g8ALrsvgSkvSUSW2bMWlH58_wPza14wi-7EsufL_zHc75suwhwS8IYdXLFuw2p5jQ-WCE3spWpOA4p5yJ29kKk4LlGJfXZ9m9GFucnpzKu9kZpZJhLuUq-3URo7dOj84PyDfIm-Q5uj10B9SDjlOAGu22h-is7pCeJTce0A83bhHEUZvOxW1C9FCjwacyZHWond_raKdOB2Sc73X4BiEiNyDoagjJOk5_-sRXCPYQ0n-EHbJ-GsZ4P7vT6C7Cg-N9nn158_py_S7ffHz7fn2xyU0hqjEXRktT8kZjWzWkBsopFKzmhhloJNEUgOGy4LpgUmKp65oTY2vNsLASC2Dn2bPFdxf89ynNonoXLXSdHsBPUREhCC9JScnNKBVlUVFRiYQ--Q9t_RSGNIginEsqGK5kovBC2eBjDNCoXXBpTQdFsJqTVXOyak5WLcmmksdH48n0UJ8K_kaZgKdHIK1ed03Qg3XxH1dxUXJWJu7RwrVx9OGkF4wKUshZzxfdpVB-nvSUoao446X6cLVWV3j96frz5qu6TPzzhTd9e_MYvwHxbNXQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1779283069</pqid></control><display><type>article</type><title>Association of objectively measured physical activity with established and novel cardiovascular biomarkers in elderly subjects: every step counts</title><source>JSTOR Archival Journals and Primary Sources Collection</source><source>BMJ Journals</source><creator>Klenk, Jochen ; Denkinger, Michael ; Nikolaus, Thorsten ; Peter, Richard ; Rothenbacher, Dietrich ; Koenig, Wolfgang</creator><creatorcontrib>Klenk, Jochen ; Denkinger, Michael ; Nikolaus, Thorsten ; Peter, Richard ; Rothenbacher, Dietrich ; Koenig, Wolfgang ; ActiFE Study Group ; the ActiFE Study Group</creatorcontrib><description>Objective To analyse the relationship between objectively measured daily walking duration and cardiovascular biomarkers of inflammation, cardiac dysfunction and renal impairment. Methods Between March 2009 and April 2010, physical activity was assessed in 1253 community-dwelling individuals living in Germany aged ≥65 years (57% men) over 1 week using a thigh-worn accelerometer. C reactive protein (CRP), white blood cells (WBC), N-terminal pro-brain natriuretic peptide, high-sensitive troponin T (hsTnT), creatinine (Cr) and cystatin C (CysC) were also measured. Least-square means of daily walking duration were calculated for quartiles of each biomarker adjusted for sex, age, pre-existing cardiovascular disease and smoking status. Results After adjustment for covariates, statistically significant linear associations with walking duration were observed for WBC, hsTnT, Cr and CysC. CRP quartiles 1 and 2 showed no significant difference followed by a significant inverse dose–response relationship. A similar pattern, but less pronounced, was seen for N-terminal pro-brain natriuretic peptide. Mean differences between the first two quartiles of CRP and its fourth quartile were 17 min. Between categories 1 (more beneficial) and 4 of WBC, hsTnT, Cr and CysC the differences were 15, 12, 23 and 20 min, respectively. Conclusion Increased walking duration is associated with a more favourable profile of cardiovascular biomarkers in elderly subjects.</description><identifier>ISSN: 0143-005X</identifier><identifier>EISSN: 1470-2738</identifier><identifier>DOI: 10.1136/jech-2012-201312</identifier><identifier>PMID: 22930799</identifier><identifier>CODEN: JECHDR</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Activities of Daily Living ; Activity ; Aged ; Aged, 80 and over ; ageing ; Biological and medical sciences ; Biological markers ; biomarker ; Biomarkers - blood ; C-Reactive Protein - analysis ; cancer: breast ; cardiovascular ; Cardiovascular diseases ; Cardiovascular Diseases - blood ; Cohort Studies ; coronary heart disease ; diabetes ; elderly ; Epidemiology ; Exercise ; Female ; General aspects ; Germany ; Health risk assessment ; Heart attacks ; Humans ; Inflammation ; Inflammation - blood ; Internal medicine ; Male ; Medical sciences ; methodology ; Miscellaneous ; Mortality ; Motor Activity ; Natriuretic Peptide, Brain - blood ; Natriuretic peptides ; Older adults ; Peptide Fragments - blood ; physical activity ; Population Surveillance ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; renal ; Renal function ; Renal Insufficiency - blood ; Risk Factors ; Short report ; Studies ; Time Factors ; Troponin I - blood ; Walking ; Walking - physiology</subject><ispartof>Journal of epidemiology and community health (1979), 2013-02, Vol.67 (2), p.194-197</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>2013 BMJ Publishing Group</rights><rights>2014 INIST-CNRS</rights><rights>Copyright: 2013 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b486t-8ba9b57fa0c6f1de272e43d7b3bef91a2ee30547a439909add71bcda308c908e3</citedby><cites>FETCH-LOGICAL-b486t-8ba9b57fa0c6f1de272e43d7b3bef91a2ee30547a439909add71bcda308c908e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jech.bmj.com/content/67/2/194.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://jech.bmj.com/content/67/2/194.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>112,113,314,780,784,3194,27924,27925,58238,58471,77594,77595</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26785735$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22930799$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Klenk, Jochen</creatorcontrib><creatorcontrib>Denkinger, Michael</creatorcontrib><creatorcontrib>Nikolaus, Thorsten</creatorcontrib><creatorcontrib>Peter, Richard</creatorcontrib><creatorcontrib>Rothenbacher, Dietrich</creatorcontrib><creatorcontrib>Koenig, Wolfgang</creatorcontrib><creatorcontrib>ActiFE Study Group</creatorcontrib><creatorcontrib>the ActiFE Study Group</creatorcontrib><title>Association of objectively measured physical activity with established and novel cardiovascular biomarkers in elderly subjects: every step counts</title><title>Journal of epidemiology and community health (1979)</title><addtitle>J Epidemiol Community Health</addtitle><description>Objective To analyse the relationship between objectively measured daily walking duration and cardiovascular biomarkers of inflammation, cardiac dysfunction and renal impairment. Methods Between March 2009 and April 2010, physical activity was assessed in 1253 community-dwelling individuals living in Germany aged ≥65 years (57% men) over 1 week using a thigh-worn accelerometer. C reactive protein (CRP), white blood cells (WBC), N-terminal pro-brain natriuretic peptide, high-sensitive troponin T (hsTnT), creatinine (Cr) and cystatin C (CysC) were also measured. Least-square means of daily walking duration were calculated for quartiles of each biomarker adjusted for sex, age, pre-existing cardiovascular disease and smoking status. Results After adjustment for covariates, statistically significant linear associations with walking duration were observed for WBC, hsTnT, Cr and CysC. CRP quartiles 1 and 2 showed no significant difference followed by a significant inverse dose–response relationship. A similar pattern, but less pronounced, was seen for N-terminal pro-brain natriuretic peptide. Mean differences between the first two quartiles of CRP and its fourth quartile were 17 min. Between categories 1 (more beneficial) and 4 of WBC, hsTnT, Cr and CysC the differences were 15, 12, 23 and 20 min, respectively. Conclusion Increased walking duration is associated with a more favourable profile of cardiovascular biomarkers in elderly subjects.</description><subject>Activities of Daily Living</subject><subject>Activity</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>ageing</subject><subject>Biological and medical sciences</subject><subject>Biological markers</subject><subject>biomarker</subject><subject>Biomarkers - blood</subject><subject>C-Reactive Protein - analysis</subject><subject>cancer: breast</subject><subject>cardiovascular</subject><subject>Cardiovascular diseases</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cohort Studies</subject><subject>coronary heart disease</subject><subject>diabetes</subject><subject>elderly</subject><subject>Epidemiology</subject><subject>Exercise</subject><subject>Female</subject><subject>General aspects</subject><subject>Germany</subject><subject>Health risk assessment</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Inflammation - blood</subject><subject>Internal medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>methodology</subject><subject>Miscellaneous</subject><subject>Mortality</subject><subject>Motor Activity</subject><subject>Natriuretic Peptide, Brain - blood</subject><subject>Natriuretic peptides</subject><subject>Older adults</subject><subject>Peptide Fragments - blood</subject><subject>physical activity</subject><subject>Population Surveillance</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>renal</subject><subject>Renal function</subject><subject>Renal Insufficiency - blood</subject><subject>Risk Factors</subject><subject>Short report</subject><subject>Studies</subject><subject>Time Factors</subject><subject>Troponin I - blood</subject><subject>Walking</subject><subject>Walking - physiology</subject><issn>0143-005X</issn><issn>1470-2738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqFkduL1DAUxoso7rj67osSEEGQai5tk_i2DN5g8ALrsvgSkvSUSW2bMWlH58_wPza14wi-7EsufL_zHc75suwhwS8IYdXLFuw2p5jQ-WCE3spWpOA4p5yJ29kKk4LlGJfXZ9m9GFucnpzKu9kZpZJhLuUq-3URo7dOj84PyDfIm-Q5uj10B9SDjlOAGu22h-is7pCeJTce0A83bhHEUZvOxW1C9FCjwacyZHWond_raKdOB2Sc73X4BiEiNyDoagjJOk5_-sRXCPYQ0n-EHbJ-GsZ4P7vT6C7Cg-N9nn158_py_S7ffHz7fn2xyU0hqjEXRktT8kZjWzWkBsopFKzmhhloJNEUgOGy4LpgUmKp65oTY2vNsLASC2Dn2bPFdxf89ynNonoXLXSdHsBPUREhCC9JScnNKBVlUVFRiYQ--Q9t_RSGNIginEsqGK5kovBC2eBjDNCoXXBpTQdFsJqTVXOyak5WLcmmksdH48n0UJ8K_kaZgKdHIK1ed03Qg3XxH1dxUXJWJu7RwrVx9OGkF4wKUshZzxfdpVB-nvSUoao446X6cLVWV3j96frz5qu6TPzzhTd9e_MYvwHxbNXQ</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Klenk, Jochen</creator><creator>Denkinger, Michael</creator><creator>Nikolaus, Thorsten</creator><creator>Peter, Richard</creator><creator>Rothenbacher, Dietrich</creator><creator>Koenig, Wolfgang</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7TS</scope></search><sort><creationdate>20130201</creationdate><title>Association of objectively measured physical activity with established and novel cardiovascular biomarkers in elderly subjects: every step counts</title><author>Klenk, Jochen ; Denkinger, Michael ; Nikolaus, Thorsten ; Peter, Richard ; Rothenbacher, Dietrich ; Koenig, Wolfgang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b486t-8ba9b57fa0c6f1de272e43d7b3bef91a2ee30547a439909add71bcda308c908e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Activities of Daily Living</topic><topic>Activity</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>ageing</topic><topic>Biological and medical sciences</topic><topic>Biological markers</topic><topic>biomarker</topic><topic>Biomarkers - blood</topic><topic>C-Reactive Protein - analysis</topic><topic>cancer: breast</topic><topic>cardiovascular</topic><topic>Cardiovascular diseases</topic><topic>Cardiovascular Diseases - blood</topic><topic>Cohort Studies</topic><topic>coronary heart disease</topic><topic>diabetes</topic><topic>elderly</topic><topic>Epidemiology</topic><topic>Exercise</topic><topic>Female</topic><topic>General aspects</topic><topic>Germany</topic><topic>Health risk assessment</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Inflammation - blood</topic><topic>Internal medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>methodology</topic><topic>Miscellaneous</topic><topic>Mortality</topic><topic>Motor Activity</topic><topic>Natriuretic Peptide, Brain - blood</topic><topic>Natriuretic peptides</topic><topic>Older adults</topic><topic>Peptide Fragments - blood</topic><topic>physical activity</topic><topic>Population Surveillance</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>renal</topic><topic>Renal function</topic><topic>Renal Insufficiency - blood</topic><topic>Risk Factors</topic><topic>Short report</topic><topic>Studies</topic><topic>Time Factors</topic><topic>Troponin I - blood</topic><topic>Walking</topic><topic>Walking - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Klenk, Jochen</creatorcontrib><creatorcontrib>Denkinger, Michael</creatorcontrib><creatorcontrib>Nikolaus, Thorsten</creatorcontrib><creatorcontrib>Peter, Richard</creatorcontrib><creatorcontrib>Rothenbacher, Dietrich</creatorcontrib><creatorcontrib>Koenig, Wolfgang</creatorcontrib><creatorcontrib>ActiFE Study Group</creatorcontrib><creatorcontrib>the ActiFE Study Group</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Physical Education Index</collection><jtitle>Journal of epidemiology and community health (1979)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Klenk, Jochen</au><au>Denkinger, Michael</au><au>Nikolaus, Thorsten</au><au>Peter, Richard</au><au>Rothenbacher, Dietrich</au><au>Koenig, Wolfgang</au><aucorp>ActiFE Study Group</aucorp><aucorp>the ActiFE Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of objectively measured physical activity with established and novel cardiovascular biomarkers in elderly subjects: every step counts</atitle><jtitle>Journal of epidemiology and community health (1979)</jtitle><addtitle>J Epidemiol Community Health</addtitle><date>2013-02-01</date><risdate>2013</risdate><volume>67</volume><issue>2</issue><spage>194</spage><epage>197</epage><pages>194-197</pages><issn>0143-005X</issn><eissn>1470-2738</eissn><coden>JECHDR</coden><abstract>Objective To analyse the relationship between objectively measured daily walking duration and cardiovascular biomarkers of inflammation, cardiac dysfunction and renal impairment. Methods Between March 2009 and April 2010, physical activity was assessed in 1253 community-dwelling individuals living in Germany aged ≥65 years (57% men) over 1 week using a thigh-worn accelerometer. C reactive protein (CRP), white blood cells (WBC), N-terminal pro-brain natriuretic peptide, high-sensitive troponin T (hsTnT), creatinine (Cr) and cystatin C (CysC) were also measured. Least-square means of daily walking duration were calculated for quartiles of each biomarker adjusted for sex, age, pre-existing cardiovascular disease and smoking status. Results After adjustment for covariates, statistically significant linear associations with walking duration were observed for WBC, hsTnT, Cr and CysC. CRP quartiles 1 and 2 showed no significant difference followed by a significant inverse dose–response relationship. A similar pattern, but less pronounced, was seen for N-terminal pro-brain natriuretic peptide. Mean differences between the first two quartiles of CRP and its fourth quartile were 17 min. Between categories 1 (more beneficial) and 4 of WBC, hsTnT, Cr and CysC the differences were 15, 12, 23 and 20 min, respectively. Conclusion Increased walking duration is associated with a more favourable profile of cardiovascular biomarkers in elderly subjects.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>22930799</pmid><doi>10.1136/jech-2012-201312</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0143-005X |
| ispartof | Journal of epidemiology and community health (1979), 2013-02, Vol.67 (2), p.194-197 |
| issn | 0143-005X 1470-2738 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1881751521 |
| source | JSTOR Archival Journals and Primary Sources Collection; BMJ Journals |
| subjects | Activities of Daily Living Activity Aged Aged, 80 and over ageing Biological and medical sciences Biological markers biomarker Biomarkers - blood C-Reactive Protein - analysis cancer: breast cardiovascular Cardiovascular diseases Cardiovascular Diseases - blood Cohort Studies coronary heart disease diabetes elderly Epidemiology Exercise Female General aspects Germany Health risk assessment Heart attacks Humans Inflammation Inflammation - blood Internal medicine Male Medical sciences methodology Miscellaneous Mortality Motor Activity Natriuretic Peptide, Brain - blood Natriuretic peptides Older adults Peptide Fragments - blood physical activity Population Surveillance Public health. Hygiene Public health. Hygiene-occupational medicine renal Renal function Renal Insufficiency - blood Risk Factors Short report Studies Time Factors Troponin I - blood Walking Walking - physiology |
| title | Association of objectively measured physical activity with established and novel cardiovascular biomarkers in elderly subjects: every step counts |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T03%3A23%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20of%20objectively%20measured%20physical%20activity%20with%20established%20and%20novel%20cardiovascular%20biomarkers%20in%20elderly%20subjects:%20every%20step%20counts&rft.jtitle=Journal%20of%20epidemiology%20and%20community%20health%20(1979)&rft.au=Klenk,%20Jochen&rft.aucorp=ActiFE%20Study%20Group&rft.date=2013-02-01&rft.volume=67&rft.issue=2&rft.spage=194&rft.epage=197&rft.pages=194-197&rft.issn=0143-005X&rft.eissn=1470-2738&rft.coden=JECHDR&rft_id=info:doi/10.1136/jech-2012-201312&rft_dat=%3Cjstor_proqu%3E43281495%3C/jstor_proqu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-b486t-8ba9b57fa0c6f1de272e43d7b3bef91a2ee30547a439909add71bcda308c908e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1779283069&rft_id=info:pmid/22930799&rft_jstor_id=43281495&rfr_iscdi=true |