Ratio of Systolic Blood Pressure to Right Atrial Pressure, a Novel Marker to Predict Morbidity and Mortality in Acute Systolic Heart Failure

Congestion is the main contributor to heart failure (HF) morbidity and mortality. We assessed the combined role of congestion and decreased forward flow in predicting morbidity and mortality in acute systolic HF. The Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization E...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of cardiology 2017-04, Vol.119 (7), p.1061-1068
Main Authors: Omar, Hesham R., MD, Charnigo, Richard, PhD, Guglin, Maya, MD
Format: Article
Language:English
Subjects:
Acute Disease
Atrial Pressure - physiology
Biomarkers - analysis
Blood pressure
Blood Pressure - physiology
Body mass index
Cardiovascular
Female
Heart failure
Heart Failure - mortality
Heart Failure - physiopathology
Hospitalization - statistics & numerical data
Humans
Intubation
Laboratories
Male
Middle Aged
Morbidity
Mortality
Optimism
Patient Readmission - statistics & numerical data
Predictive Value of Tests
Pulmonary arteries
Risk Factors
Sensitivity and Specificity
Systole
Variables
Veins & arteries
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Congestion is the main contributor to heart failure (HF) morbidity and mortality. We assessed the combined role of congestion and decreased forward flow in predicting morbidity and mortality in acute systolic HF. The Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness trial data set was used to determine if the ratio of simultaneously measured systolic blood pressure (SBP)/right atrial pressure (RAP) on admission predicted HF rehospitalization and 6-month mortality. One hundred ninety-five patients (mean age 56.5 years, 75% men) who received pulmonary artery catheterization were studied. The RAP, SBP, and SBP/RAP had an area under the curve (AUC) of 0.593 (p = 0.0205), 0.585 (p = 0.0359), and 0.621 (p = 0.0026), respectively, in predicting HF rehospitalization. The SBP/RAP was a superior marker of HF rehospitalization compared with RAP alone (difference in AUC 0.0289, p = 0.0385). The optimal criterion of SBP/RAP
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2016.11.062