Colutin, new antifungal isoflavan from Colutea armata

A new isoflavan, colutin ( 1 ), has been isolated from the EtOAc soluble fraction of the MeOH extract of Colutea armata, along with three known compounds, sativan ( 2 ), isovestitol ( 3 ), and cinnamic acid ( 4 ), isolated for the first time from this species. Their structures were elucidated by spe...

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Bibliographic Details
Published in:Chemistry of natural compounds 2016-07, Vol.52 (4), p.611-614
Main Authors: Shakeel, Unber, Inamullah, Farah, Fatima, Itrat, Khan, Sadia, Kazmi, Mehdi Hassan, Malik, Abdul, Tareen, Rasool Bakhsh, Abbas, Tanvir
Format: Article
Language:English
Subjects:
Antifungal agents
Colutea
Medicine
Organic Chemistry
Pharmacy
Plant Sciences
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Summary:A new isoflavan, colutin ( 1 ), has been isolated from the EtOAc soluble fraction of the MeOH extract of Colutea armata, along with three known compounds, sativan ( 2 ), isovestitol ( 3 ), and cinnamic acid ( 4 ), isolated for the first time from this species. Their structures were elucidated by spectroscopic techniques including two-dimensional NMR. Colutin ( 1 ) showed significant antifungal activity.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-016-1722-4