Rivaroxaban Rebound Acute Coronary Event: A Post Marketing Experience

We present a 65-year-old male who received rivaroxaban therapy prior to and after left knee replacement surgery. The patient developed generalized weakness soon after stopping rivaroxaban. An electrocardiogram showed acute infero-lateral ischemia and an echocardiogram reported an akinetic antero-api...

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Bibliographic Details
Published in:Cardiology research 2013, Vol.4 (6), p.207-210
Main Authors: Agarwal, Ajay, Patel, Amish, Mufti, Omar, Jbara, Yaser, Jabbar, Ali Abdul
Format: Report
Language:English
Online Access:Get full text
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Summary:We present a 65-year-old male who received rivaroxaban therapy prior to and after left knee replacement surgery. The patient developed generalized weakness soon after stopping rivaroxaban. An electrocardiogram showed acute infero-lateral ischemia and an echocardiogram reported an akinetic antero-apical wall segment, an apical clot and a reduced systolic function. A subsequent coronary angiogram revealed two-vessel coronary artery thrombosis. The case illustrates a temporal relationship of coronary thrombosis following rivaroxaban cessation.
ISSN:1923-2829
DOI:10.4021/cr294w