Stress response in a juvenile hormone-deficient Drosophila melanogaster mutant apterous super(56f)

The apterous super(56f) (ap super(56f)) mutation leads to increases in juvenile hormone (JH) degradation levels and JH-esterase makes a greater contribution to the increase than JH-epoxide hydrolase. Dopamine levels in ap super(56f) females, but not males, are higher than in wild-type. JH treatment...

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Bibliographic Details
Published in:Insect molecular biology 2003-08, Vol.12 (4), p.353-363
Main Authors: Gruntenko, N E, Chentsova, NA, Andreenkova, E V, Bownes, M, Segal, D, Adonyeva, N V, Rauschenbach, I Y
Format: Article
Language:English
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Summary:The apterous super(56f) (ap super(56f)) mutation leads to increases in juvenile hormone (JH) degradation levels and JH-esterase makes a greater contribution to the increase than JH-epoxide hydrolase. Dopamine levels in ap super(56f) females, but not males, are higher than in wild-type. JH treatment of ap super(56f) and wild-type females decreases their dopamine levels. ap super(56f) females, but not males, produce less progeny. Survival under heat stress is dramatically decreased in ap super(56f) females, but not males. ap super(56f) flies show a stress reaction, as judged by changes in tyrosine decarboxylase and JH-hydrolysing activities, dopamine levels and fertility, but its intensity in the mutant females, but not males, differs significantly from wild-type. Thus, the ap super(56f) mutation causes dramatic changes in female, but not male, metabolism and fitness.
ISSN:0962-1075
DOI:10.1046/j.1365-2583.2003.00419.x