Extensive lymph node dissection during pancreaticoduodenectomy: a risk factor for hepatic steatosis?

s Purpose The first reports of hepatic steatosis following pancreaticoduodenectomy (PD) were published several years ago; however, clear risk factors remain to be identified. Therefore, the aim of this study was to identify the risk factors for hepatic steatosis post-PD. Methods We studied 90 patien...

Full description

Saved in:
Bibliographic Details
Published in:Abdominal imaging 2017-07, Vol.42 (7), p.1880-1887
Main Authors: Mignot, A., Ayav, A., Quillot, D., Zuily, S., Petit, I., Nguyen-Thi, P. L., Malgras, A., Laurent, V.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biopsy
Chemotherapy
Computed tomography
Density
Dissection
Fatty liver
Fatty Liver - diagnostic imaging
Fatty Liver - epidemiology
Female
Gastroenterology
Hepatology
Humans
Identification methods
Imaging
Liver
Lymph
Lymph Node Excision
Lymph nodes
Lymphatic Metastasis
Lymphatic system
Male
Medicine
Medicine & Public Health
Middle Aged
Multivariate analysis
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - surgery
Pancreaticoduodenectomy
Patients
Portal vein
Postoperative Complications - diagnostic imaging
Postoperative Complications - epidemiology
Radiology
Retrospective Studies
Risk analysis
Risk Factors
Scanners
Spleen
Steatosis
Tomography, X-Ray Computed
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:s Purpose The first reports of hepatic steatosis following pancreaticoduodenectomy (PD) were published several years ago; however, clear risk factors remain to be identified. Therefore, the aim of this study was to identify the risk factors for hepatic steatosis post-PD. Methods We studied 90 patients who had undergone PD between September 2005 and January 2015. The inclusion criteria were as follows: available unenhanced CT within one month before PD and at least one unenhanced CT acquisition between PD and chemotherapy initiation. Using scanners, we studied the liver and spleen density as well as the surface areas of visceral (VF) and subcutaneous fat (SCF). These variables were previously identified by univariate and multivariate analyses. Results Hepatic steatosis occurred in 25.6% of patients at 45.2 days, on average, post-PD. Among the patients with hepatic steatosis, the average liver density was 52 HU before PD and 15.1 HU post-PD ( p  
ISSN:2366-004X
2366-0058
DOI:10.1007/s00261-017-1087-6