Diagnosis and Treatment of Drug-Resistant Tuberculosis

In the last 2 decades, drug-resistant tuberculosis has become a threat and a challenge to worldwide public health. The diagnosis and treatment of these forms of tuberculosis are much more complex and prognosis clearly worsens as the resistance pattern intensifies. Nevertheless, it is important to re...

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Published in:Archivos de bronconeumología (English ed.) 2017-09, Vol.53 (9), p.501-509
Main Authors: Caminero, José A, Cayla, Joan A, García-García, José-María, García-Pérez, Francisco J, Palacios, Juan J, Ruiz-Manzano, Juan
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Language:eng ; spa
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container_issue 9
container_start_page 501
container_title Archivos de bronconeumología (English ed.)
container_volume 53
creator Caminero, José A
Cayla, Joan A
García-García, José-María
García-Pérez, Francisco J
Palacios, Juan J
Ruiz-Manzano, Juan
description In the last 2 decades, drug-resistant tuberculosis has become a threat and a challenge to worldwide public health. The diagnosis and treatment of these forms of tuberculosis are much more complex and prognosis clearly worsens as the resistance pattern intensifies. Nevertheless, it is important to remember that with the appropriatesystematic clinical management, most of these patients can be cured. These guidelines itemize the basis for the diagnosis and treatment of all tuberculosis patients, from those infected by strains that are sensitive to all drugs, to those who are extensively drug-resistant. Specific recommendations are given forall cases. The current and future role of new molecular methods for detecting resistance, shorter multi-drug-resistant tuberculosis regimens, and new drugs with activity against Mycobacterium tuberculosis are also addressed.
doi_str_mv 10.1016/j.arbres.2017.02.006
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title Diagnosis and Treatment of Drug-Resistant Tuberculosis
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