A paralogous decoy protects Phytophthora sojae apoplastic effector PsXEG1 from a host inhibitor

The extracellular space (apoplast) of plant tissue represents a critical battleground between plants and attacking microbes. Here we show that a pathogen-secreted apoplastic xyloglucan-specific endoglucanase, PsXEG1, is a focus of this struggle in the Phytophthora sojae–soybean interaction. We show...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2017-02, Vol.355 (6326), p.710-714
Main Authors: Ma, Zhenchuan, Zhu, Lin, Song, Tianqiao, Wang, Yang, Zhang, Qi, Xia, Yeqiang, Qiu, Min, Lin, Yachun, Li, Haiyang, Kong, Liang, Fang, Yufeng, Ye, Wenwu, Wang, Yan, Dong, Suomeng, Zheng, Xiaobo, Tyler, Brett M., Wang, Yuanchao
Format: Article
Language:English
Subjects:
Cellulase - antagonists & inhibitors
Cellulase - genetics
Cellulase - metabolism
Damage
Decoys
Effectors
Endoglucanase
Enzyme activity
Enzymes
Extracellular Space - parasitology
Genes
Glucans - metabolism
Glycine max
Glycine max - enzymology
Glycine max - genetics
Glycine max - parasitology
Host-Pathogen Interactions
Infections
Inhibitors
Microorganisms
Oomycetes
Pathogens
Phytophthora
Phytophthora - enzymology
Phytophthora - genetics
Phytophthora - pathogenicity
Phytophthora parasitica
Phytophthora sojae
Plant Diseases - parasitology
Plant Proteins - genetics
Plant Proteins - metabolism
Plant tissues
Plants
Protein Binding
Proteins
Soybeans
Virulence
Xylans - metabolism
Xyloglucanase
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Summary:The extracellular space (apoplast) of plant tissue represents a critical battleground between plants and attacking microbes. Here we show that a pathogen-secreted apoplastic xyloglucan-specific endoglucanase, PsXEG1, is a focus of this struggle in the Phytophthora sojae–soybean interaction. We show that soybean produces an apoplastic glucanase inhibitor protein, GmGIP1, that binds to PsXEG1 to block its contribution to virulence. P. sojae, however, secretes a paralogous PsXEG1-like protein, PsXLP1, that has lost enzyme activity but binds to GmGIP1 more tightly than does PsXEG1, thus freeing PsXEG1 to support P. sojae infection. The gene pair encoding PsXEG1 and PsXLP1 is conserved in many Phytophthora species, and the P. parasitica orthologs PpXEG1 and PpXLP1 have similar functions. Thus, this apoplastic decoy strategy may be widely used in Phytophthora pathosystems.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.aai7919