Eligibility Criteria Specific to Pancreaticoduodenectomy for Octogenarians: Single-center Opinion

• Published in: Anticancer research 2017-04, Vol.37 (4), p.2037-2043
• Main Authors: Shiozawa, Shunichi, Usui, Takebumi, Kuhara, Kotaro, Tsuchiya, Akira, Miyauchi, Tatsuomi, Kono, Teppei, Shimojima, Yukio, Asaka, Shinichi, Yamaguchi, Kentaro, Yokomizo, Hajime, Shimakawa, Takeshi, Yoshimatsu, Kazuhiko, Katsube, Takao, Naritaka, Yoshihiko
• Format: Article
• Language: English
• Subjects: Age Factors; Aged; Aged, 80 and over; Comorbidity; Female; Follow-Up Studies; Humans; Length of Stay; Male; Neoplasm Staging; Pancreatic Neoplasms - mortality; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - surgery; Pancreaticoduodenectomy - mortality; Postoperative Complications; Prognosis; Prospective Studies; Risk Factors; Survival Rate
• ISSN: 0250-7005; 1791-7530
• DOI: 10.21873/anticanres.11549

Pancreaticoduodenectomy (PD) treatment outcomes in elderly patients have been reported to be acceptable, but the eligibility criteria are not clear. To elucidate the importance of PD in octogenarians in particular, we set five eligibility criteria for elderly patients based on preoperative cardiac and pulmonary function, nutritional status, daily activity status, and psychological independence status for the first time and evaluated prospectively whether the validity of patient selection was adaptable. The study population consisted of 222 patients with pancreaticobiliary cancer aged over 70 years. The patients were divided into two groups: 192 patients as septuagenarians and 30 as octogenarians. Postoperative morbidity and long-term outcome were compared between the two groups, and prognostic factors relating to survival time were identified. Octogenarians had a significantly higher frequency of two or more comorbidities (p