Effectiveness of ledipasvir/sofosbuvir in real-world patients with chronic hepatitis C: a collaborative treatment approach

Highlights • Real-world data on the use of ledipasvir/sofosbuvir are limited. • Data support interprofessional management of hepatitis C virus. • Sustained virological response rates obtained in the study cohort were similar to those in clinical trials. • Tolerability in the study cohort was similar...

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Bibliographic Details
Published in:International journal of antimicrobial agents 2017-06, Vol.49 (6), p.778-781
Main Authors: Johnson, Steven W, Ammirati, Shelby R, Hartis, Charles E, Weber, Stephen F, Morgan, Michael R, Darnell, Timothy A, Silwal, Adwait, Schmidlin, Holly N, Priest, David H
Format: Article
Language:English
Subjects:
Adult
Aged
Antiviral Agents - adverse effects
Antiviral Agents - therapeutic use
Benzimidazoles - adverse effects
Benzimidazoles - therapeutic use
Drug-Related Side Effects and Adverse Reactions - epidemiology
Female
Fluorenes - adverse effects
Fluorenes - therapeutic use
HCV
Hepatitis C virus
Hepatitis C, Chronic - drug therapy
Humans
Infectious Disease
LDV/SOF
Ledipasvir/sofosbuvir
Male
Middle Aged
Prospective Studies
Real-life
Sustained Virologic Response
Treatment Outcome
Uridine Monophosphate - adverse effects
Uridine Monophosphate - analogs & derivatives
Uridine Monophosphate - therapeutic use
Young Adult
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Summary:Highlights • Real-world data on the use of ledipasvir/sofosbuvir are limited. • Data support interprofessional management of hepatitis C virus. • Sustained virological response rates obtained in the study cohort were similar to those in clinical trials. • Tolerability in the study cohort was similar to that in clinical trials.
ISSN:0924-8579
1872-7913
DOI:10.1016/j.ijantimicag.2017.01.016