Immune response to hepatitis B vaccination among people with inflammatory bowel diseases: A systematic review and meta-analysis

Highlights • We examine the response rate to HBV vaccination in patients with IBD. • Only three of five IBD patients will show a serological response to HBV vaccination. • Vaccination should be performed during remission, or before starting therapy.

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Bibliographic Details
Published in:Vaccine 2017-05, Vol.35 (20), p.2633-2641
Main Authors: Jiang, Hai-yin, Wang, Shu-yin, Deng, Min, Li, Yu-chuan, Ling, Zong-xin, Shao, Li, Ruan, Bing
Format: Article
Language:English
Subjects:
Allergy and Immunology
Confidence intervals
Crohn’s disease
Epidemiology
Hepatitis
Hepatitis B
Hepatitis B - prevention & control
Hepatitis B Antibodies - blood
Hepatitis B vaccine
Hepatitis B Vaccines - administration & dosage
Hepatitis B Vaccines - immunology
Hepatitis B virus - immunology
Humans
Identification methods
Immune response
Immune system
Immunomodulation
Immunosuppressive agents
Inflammatory bowel disease
Inflammatory bowel diseases
Inflammatory Bowel Diseases - complications
Intestine
Libraries
Meta-analysis
Patients
Remission
Remission (Medicine)
Systematic review
Therapy
Treatment Outcome
Tumor necrosis factor-TNF
Tumor necrosis factor-α
Ulcerative colitis
Vaccination
Viruses
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Description
Summary:Highlights • We examine the response rate to HBV vaccination in patients with IBD. • Only three of five IBD patients will show a serological response to HBV vaccination. • Vaccination should be performed during remission, or before starting therapy.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2017.03.080