Anti-Tobacco Mosaic Virus Isocoumarins from the Leaves of Nicotiana tabacum

Two new isocoumarins, tabaisocoumarins D and E ( 1 and 2 ), together with two known isocoumarins ( 3 and 4 ), were isolated from the leaves of Nicotiana tabacum . The structures of 1–4 were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1–4 were also tes...

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Bibliographic Details
Published in:Chemistry of natural compounds 2016-03, Vol.52 (2), p.218-221
Main Authors: Wang, Yuede, Wang, Xinlin, Zhu, Long, Zhang, Tiandong, Zhou, Kun, Dong, Wei, Hu, Wei-Yao, Li, Yinke, Yang, Guangyu, Min, Zhou, Hu, Qiufen
Format: Article
Language:English
Subjects:
Antismoking movement
Medicine
Nicotiana tabacum
Organic Chemistry
Pharmacy
Plant Sciences
Tobacco industry
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Summary:Two new isocoumarins, tabaisocoumarins D and E ( 1 and 2 ), together with two known isocoumarins ( 3 and 4 ), were isolated from the leaves of Nicotiana tabacum . The structures of 1–4 were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1–4 were also tested for their anti-tobacco mosaic virus (anti-TMV) activities. Compounds 1–4 exhibited anti-TMV activities with inhibition rates in the range of 11.2–17.5%.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-016-1598-3