Small Sample Sizes Confound Understanding of Cardiometabolic Responses to Exercise

Considerable variability exists in the cardiometabolic disease biomarker response to exercise. We propose that a major contributor to this heterogeneity is underpowered studies due to small sample sizes. To test our hypothesis, we conducted a systematic review to identify meta-analyses/reviews of ra...

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Bibliographic Details
Published in:Exercise and sport sciences reviews 2017-07, Vol.45 (3), p.173-180
Main Authors: Pescatello, Linda S, Corso, Lauren M L, MacDonald, Hayley V, Thompson, Paul D, Taylor, Beth A, Panza, Gregory A, Zaleski, Amanda L, Johnson, Blair T, Chen, Ming-Hui
Format: Article
Language:English
Subjects:
Biomarkers - analysis
Cardiovascular Diseases - physiopathology
Exercise - physiology
Humans
Metabolic Diseases - physiopathology
Resistance Training
Sample Size
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Summary:Considerable variability exists in the cardiometabolic disease biomarker response to exercise. We propose that a major contributor to this heterogeneity is underpowered studies due to small sample sizes. To test our hypothesis, we conducted a systematic review to identify meta-analyses/reviews of randomized controlled trials (RCT) and RCT that examined the cardiometabolic disease biomarker response to aerobic and resistance exercise.
ISSN:0091-6331
1538-3008
DOI:10.1249/JES.0000000000000115