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Determination of reference intervals of acid‐base parameters in clinically healthy dogs

Objective To establish reference intervals for traditionally‐ and Stewart's approach‐determined acid‐base parameters in a population of clinically healthy dogs. Design Prospective study (June 2011–September 2012). Setting Veterinary teaching hospital. Animals Two hundred twenty‐four client‐owne...

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Published in:Journal of veterinary emergency and critical care (San Antonio, Tex. : 2000) Tex. : 2000), 2017-05, Vol.27 (3), p.325-332
Main Authors: Vanova‐Uhrikova, Ivana, Rauserova‐Lexmaulova, Leona, Rehakova, Kristina, Scheer, Peter, Doubek, Jaroslav
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Language:English
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cited_by cdi_FETCH-LOGICAL-c3259-94579ede79505d19d089ae130a58c1b918bcfa126e5b757f6503627caf1ca8aa3
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container_issue 3
container_start_page 325
container_title Journal of veterinary emergency and critical care (San Antonio, Tex. : 2000)
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creator Vanova‐Uhrikova, Ivana
Rauserova‐Lexmaulova, Leona
Rehakova, Kristina
Scheer, Peter
Doubek, Jaroslav
description Objective To establish reference intervals for traditionally‐ and Stewart's approach‐determined acid‐base parameters in a population of clinically healthy dogs. Design Prospective study (June 2011–September 2012). Setting Veterinary teaching hospital. Animals Two hundred twenty‐four client‐owned, clinically healthy dogs. Interventions Blood was collected from the jugular vein and the dorsal pedal artery. Measurements and Main Results In the whole blood samples, pH, PCO2, and PO2 were measured and HCO3−, standard and total bicarbonate, base excess, oxygen content, and alveolar–arterial oxygen differences were calculated. Plasma sodium, potassium, chloride, calcium, albumin, and lactate concentrations were measured and the following parameters were calculated separately for venous and arterial samples: anion gap, anion gap corrected for albumin and phosphate, sodium chloride difference and ratio, chloride gap, strong ion difference, strong ion gap, and unmeasured anions. Conclusion Reference intervals for traditionally‐ and Stewart's approach‐determined acid‐base parameters were established for venous and arterial blood in dogs.
doi_str_mv 10.1111/vec.12589
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Design Prospective study (June 2011–September 2012). Setting Veterinary teaching hospital. Animals Two hundred twenty‐four client‐owned, clinically healthy dogs. Interventions Blood was collected from the jugular vein and the dorsal pedal artery. Measurements and Main Results In the whole blood samples, pH, PCO2, and PO2 were measured and HCO3−, standard and total bicarbonate, base excess, oxygen content, and alveolar–arterial oxygen differences were calculated. Plasma sodium, potassium, chloride, calcium, albumin, and lactate concentrations were measured and the following parameters were calculated separately for venous and arterial samples: anion gap, anion gap corrected for albumin and phosphate, sodium chloride difference and ratio, chloride gap, strong ion difference, strong ion gap, and unmeasured anions. Conclusion Reference intervals for traditionally‐ and Stewart's approach‐determined acid‐base parameters were established for venous and arterial blood in dogs.</description><identifier>ISSN: 1479-3261</identifier><identifier>EISSN: 1476-4431</identifier><identifier>DOI: 10.1111/vec.12589</identifier><identifier>PMID: 28420042</identifier><language>eng</language><publisher>United States</publisher><subject>Acid-Base Equilibrium ; Animals ; anion gap ; Bicarbonates - blood ; Blood Gas Analysis - veterinary ; canine ; Chlorides - blood ; Dogs - blood ; Female ; Lactic Acid - blood ; Male ; Potassium - blood ; Prospective Studies ; Reference Values ; strong ion difference ; strong ion gap ; unmeasured anions</subject><ispartof>Journal of veterinary emergency and critical care (San Antonio, Tex. : 2000), 2017-05, Vol.27 (3), p.325-332</ispartof><rights>Veterinary Emergency and Critical Care Society 2017</rights><rights>Veterinary Emergency and Critical Care Society 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3259-94579ede79505d19d089ae130a58c1b918bcfa126e5b757f6503627caf1ca8aa3</citedby><cites>FETCH-LOGICAL-c3259-94579ede79505d19d089ae130a58c1b918bcfa126e5b757f6503627caf1ca8aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28420042$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vanova‐Uhrikova, Ivana</creatorcontrib><creatorcontrib>Rauserova‐Lexmaulova, Leona</creatorcontrib><creatorcontrib>Rehakova, Kristina</creatorcontrib><creatorcontrib>Scheer, Peter</creatorcontrib><creatorcontrib>Doubek, Jaroslav</creatorcontrib><title>Determination of reference intervals of acid‐base parameters in clinically healthy dogs</title><title>Journal of veterinary emergency and critical care (San Antonio, Tex. : 2000)</title><addtitle>J Vet Emerg Crit Care (San Antonio)</addtitle><description>Objective To establish reference intervals for traditionally‐ and Stewart's approach‐determined acid‐base parameters in a population of clinically healthy dogs. Design Prospective study (June 2011–September 2012). Setting Veterinary teaching hospital. Animals Two hundred twenty‐four client‐owned, clinically healthy dogs. Interventions Blood was collected from the jugular vein and the dorsal pedal artery. Measurements and Main Results In the whole blood samples, pH, PCO2, and PO2 were measured and HCO3−, standard and total bicarbonate, base excess, oxygen content, and alveolar–arterial oxygen differences were calculated. Plasma sodium, potassium, chloride, calcium, albumin, and lactate concentrations were measured and the following parameters were calculated separately for venous and arterial samples: anion gap, anion gap corrected for albumin and phosphate, sodium chloride difference and ratio, chloride gap, strong ion difference, strong ion gap, and unmeasured anions. 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subjects Acid-Base Equilibrium
Animals
anion gap
Bicarbonates - blood
Blood Gas Analysis - veterinary
canine
Chlorides - blood
Dogs - blood
Female
Lactic Acid - blood
Male
Potassium - blood
Prospective Studies
Reference Values
strong ion difference
strong ion gap
unmeasured anions
title Determination of reference intervals of acid‐base parameters in clinically healthy dogs
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