Global longitudinal strain from resting echocardiogram is associated with long-term adverse cardiac outcomes in patients with suspected coronary artery disease

Purpose: Measuring myocardial strain using two-dimensional speckle tracking echocardiography has emerged as a new tool to identify subclinical ventricular dysfunction. Abnormal strain has been shown to have superior sensitivity compared with dobutamine stress echocardiography for viability assessmen...

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Bibliographic Details
Published in:Perfusion 2017-10, Vol.32 (7), p.529-537
Main Authors: Yadlapati, Ajay, Maher, Timothy R., Thomas, James D., Gajjar, Mark, Ogunyankin, Kofo O., Puthumana, Jyothy J.
Format: Article
Language:English
Subjects:
Angiography
Cardiovascular disease
Coronary artery
Coronary artery disease
Coronary Artery Disease - complications
Coronary Artery Disease - diagnostic imaging
Echocardiography
Echocardiography, Stress - adverse effects
Echocardiography, Stress - methods
Ejection
Female
Heart diseases
Humans
Male
Middle Aged
Patients
Predictions
Risk Assessment
Sensitivity analysis
Stents
Stress
Stresses
Ultrasonic imaging
Ventricle
Viability
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Summary:Purpose: Measuring myocardial strain using two-dimensional speckle tracking echocardiography has emerged as a new tool to identify subclinical ventricular dysfunction. Abnormal strain has been shown to have superior sensitivity compared with dobutamine stress echocardiography for viability assessment; however, there is a paucity of data regarding the prediction of long-term major adverse cardiac events. We compared the prognostic ability of both global longitudinal strain (GLS) from resting echocardiograms to regional wall motion score index (WMSI) from stress echocardiograms in their ability to predict long-term major adverse cardiac events. Methods: Patients referred for stress echocardiography, who also underwent coronary angiography within 3 months of stress echo (n=122), were enrolled. Patients with reduced ejection fractions (
ISSN:0267-6591
1477-111X
DOI:10.1177/0267659117701563