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The Hemodynamic Effects of Aortic Insufficiency in Patients Supported with Continuous-Flow Left Ventricular Assist Devices

Highlights • LVAD patients with AI have elevated filling pressures and reduced PAPi. • Elevated PCWP in the presence of AI can be reduced with increased LVAD speed. • Increasing LVAD speed results in worsening AI with unknown long-term consequences.

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Published in:Journal of cardiac failure 2017-07, Vol.23 (7), p.545-551
Main Authors: Sayer, Gabriel, MD, Sarswat, Nitasha, MD, Kim, Gene H, MD, Adatya, Sirtaz, MD, Medvedofsky, Diego, MD, Rodgers, Daniel, BA, Kruse, Eric, BS, RDCS, Ota, Takeyoshi, MD PhD, Jeevanandam, Valluvan, MD, Lang, Roberto, MD, Uriel, Nir, MD MSc
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cited_by cdi_FETCH-LOGICAL-c423t-13a215d64111addb08ab56428f3fccf0f25d61c27bd0cd8c7b9f7d271b572b9f3
cites cdi_FETCH-LOGICAL-c423t-13a215d64111addb08ab56428f3fccf0f25d61c27bd0cd8c7b9f7d271b572b9f3
container_end_page 551
container_issue 7
container_start_page 545
container_title Journal of cardiac failure
container_volume 23
creator Sayer, Gabriel, MD
Sarswat, Nitasha, MD
Kim, Gene H, MD
Adatya, Sirtaz, MD
Medvedofsky, Diego, MD
Rodgers, Daniel, BA
Kruse, Eric, BS, RDCS
Ota, Takeyoshi, MD PhD
Jeevanandam, Valluvan, MD
Lang, Roberto, MD
Uriel, Nir, MD MSc
description Highlights • LVAD patients with AI have elevated filling pressures and reduced PAPi. • Elevated PCWP in the presence of AI can be reduced with increased LVAD speed. • Increasing LVAD speed results in worsening AI with unknown long-term consequences.
doi_str_mv 10.1016/j.cardfail.2017.04.012
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source ScienceDirect Journals
subjects Adult
Aged
Aortic insufficiency
Aortic Valve Insufficiency - diagnostic imaging
Aortic Valve Insufficiency - physiopathology
Aortic Valve Insufficiency - therapy
Cardiovascular
Cohort Studies
Female
Heart-Assist Devices - trends
hemodynamics
Hemodynamics - physiology
Humans
left ventricular assist device
Male
Middle Aged
right ventricular failure
Ventricular Function, Left - physiology
title The Hemodynamic Effects of Aortic Insufficiency in Patients Supported with Continuous-Flow Left Ventricular Assist Devices
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