Radiation dose reduction in parasinus CT by spectral shaping

Introduction Spectral shaping aims to narrow the X-ray spectrum of clinical CT. The aim of this study was to determine the image quality and the extent of radiation dose reduction that can be achieved by tin prefiltration for parasinus CT. Methods All scans were performed with a third generation dua...

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Bibliographic Details
Published in:Neuroradiology 2017-02, Vol.59 (2), p.169-176
Main Authors: May, Matthias S, Brand, Michael, Lell, Michael M, Sedlmair, Martin, Allmendinger, Thomas, Uder, Michael, Wuest, Wolfgang
Format: Article
Language:English
Subjects:
Dosimetry
Female
Head and Neck Radiology
Humans
Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Monte Carlo Method
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Paranasal Sinus Diseases - diagnostic imaging
Radiation
Radiation Dosage
Radiation protection
Radiation Protection - methods
Radiographic Image Interpretation, Computer-Assisted - methods
Radiology
Tin
Tomography
Tomography, X-Ray Computed - methods
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Summary:Introduction Spectral shaping aims to narrow the X-ray spectrum of clinical CT. The aim of this study was to determine the image quality and the extent of radiation dose reduction that can be achieved by tin prefiltration for parasinus CT. Methods All scans were performed with a third generation dual-source CT scanner. A study protocol was designed using 100 kV tube voltage with tin prefiltration (200 mAs) that provides image noise levels comparable to a low-dose reference protocol using 100 kV without spectral shaping (25 mAs). One hundred consecutive patients were prospectively enrolled and randomly assigned to the study or control group. All patients signed written informed consent. The study protocol was approved by the local Institutional Review Board and applies to the HIPAA. Subjective and objective image quality (attenuation values, image noise, and contrast-to-noise ratio (CNR)) were assessed. Radiation exposure was assessed as volumetric CT dose index, and effective dose was estimated. Mann-Whitney U test was performed for radiation exposure and for image noise comparison. Results All scans were of diagnostic image quality. Image noise in air, in the retrobulbar fat, and in the eye globe was comparable between both groups (all p  > 0.05). CNR eye globe/air did not differ significantly between both groups ( p  = 0.7). Radiation exposure (1.7 vs. 2.1 mGy, p  
ISSN:0028-3940
1432-1920
DOI:10.1007/s00234-016-1780-0