Weight changes in Alzheimer's disease patients with increased aberrant motor behavior

Objective Weight loss and behavioral disturbances are frequent over the course of Alzheimer's disease (AD) and are risk factors for poor outcome. We investigated the impact of aberrant motor behavior (AMB) on weight changes in older adults with AD. The hypothesis that patients with AMB are more...

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Bibliographic Details
Published in:International journal of geriatric psychiatry 2013-10, Vol.28 (10), p.998-1004
Main Authors: Secher, Marion, Andrieu, Sandrine, Gillette-Guyonnet, Sophie, Soto, Maria, Rolland, Yves, Cantet, Christelle, Vellas, Bruno, Ritz, Patrick
Format: Article
Language:English
Subjects:
aberrant motor behavior
Aged
Aged, 80 and over
Alzheimer Disease - physiopathology
Alzheimer's disease
Biological and medical sciences
Body Weight - physiology
body weight changes
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Emotions
Female
General aspects
Geriatric psychiatry
Geriatrics
Humans
Male
Medical sciences
Motor Activity - physiology
Neurology
Neuropsychology
Older people
Prospective Studies
Psychiatric Status Rating Scales
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Risk factors
wandering
Weight control
Weight Gain - physiology
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Summary:Objective Weight loss and behavioral disturbances are frequent over the course of Alzheimer's disease (AD) and are risk factors for poor outcome. We investigated the impact of aberrant motor behavior (AMB) on weight changes in older adults with AD. The hypothesis that patients with AMB are more likely to lose weight than patients without AMB was assessed. Methods A prospective study of 686 patients with moderate AD from the REAL.FR cohort was assessed. The AMB at baseline was defined by the item 10 from the Neuropsychiatric Inventory scale (NPI‐10). Patients were classified as “no or light AMB” (NPI‐10 
ISSN:0885-6230
1099-1166
DOI:10.1002/gps.3914