Pre-hospital Delay after Acute Ischemic Stroke in Central Urban China: Prevalence and Risk Factors

Timely thrombolytic treatment is paramount after acute ischemic stroke (AIS); however, a large proportion of patients experience substantial delays in presentation to hospital. This study evaluates the prevalence and risk factors in pre-hospital delays after AIS in central urban China. AIS patients...

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Bibliographic Details
Published in:Molecular neurobiology 2017-05, Vol.54 (4), p.3007-3016
Main Authors: Zhou, Yanfeng, Yang, Tingting, Gong, Yanhong, Li, Wenzhen, Chen, Yawen, Li, Jing, Wang, Mengdie, Yin, Xiaoxv, Hu, Bo, Lu, Zuxun
Format: Article
Language:English
Subjects:
Aged
Biomedical and Life Sciences
Biomedicine
Brain Ischemia - epidemiology
Cell Biology
China - epidemiology
Cities - epidemiology
Demography
Female
Hospitalization
Hospitals - statistics & numerical data
Humans
Ischemia
Logistic Models
Male
Middle Aged
Neurobiology
Neurology
Neurosciences
Prevalence
Risk Factors
Socioeconomic Factors
Stroke
Stroke - epidemiology
Urban areas
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Summary:Timely thrombolytic treatment is paramount after acute ischemic stroke (AIS); however, a large proportion of patients experience substantial delays in presentation to hospital. This study evaluates the prevalence and risk factors in pre-hospital delays after AIS in central urban China. AIS patients from 66 hospitals in 13 major cities across Hubei Province, between October 1, 2014 and January 31, 2015 were interviewed and their medical records were reviewed to identify those who suffered pre-hospital delays. Bivariate and multivariate analyses were undertaken to determine the prevalence rates and the risk factors associated with pre-hospital delays. A total of 1835 patients were included in the analysis, with 69.3 % patients reportedly arrived at hospital 3 or more hours after onset and 55.3 % patients arrived 6 or more hours after onset. Factors associated with increased pre-hospital delays for 3 or more hours were as follows: patient had a history of stroke (odds ratio (OR), 1.319, P  = 0.028), onset location was at home (OR, 1.573, P  = 0.002), and patients rather than someone else noticed the symptom onset first (OR, 1.711; P  
ISSN:0893-7648
1559-1182
DOI:10.1007/s12035-016-9750-4