Recent Advances in Boron‐Substituted 1,3‐Dienes Chemistry: Synthesis and Application

In the syntheses developed to access naturally occurring compounds, especially bioactive substances, boron‐functionalized dienes (also “linchpin” reagents) are used as key reagents. Structurally unique dienes are found in nature, and play important biological and chemical roles. Recently, linchpin m...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry : a European journal 2017-03, Vol.23 (15), p.3502-3541
Main Authors: Pyziak, Jadwiga, Walkowiak, Jędrzej, Marciniec, Bogdan
Format: Article
Language:English
Subjects:
Biological activity
Boron
Chemistry
diene
Dienes
linchpin reagents
Natural products
Organic chemistry
polyene compounds
Reagents
Synthesis (chemistry)
Transformations
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the syntheses developed to access naturally occurring compounds, especially bioactive substances, boron‐functionalized dienes (also “linchpin” reagents) are used as key reagents. Structurally unique dienes are found in nature, and play important biological and chemical roles. Recently, linchpin moieties have been proved as useful substrates for a variety of highly functionalized chemical transformations. The products of these processes are potentially of some use for the syntheses of an important class of natural products showing a wide range of biological activities. This review describes progress in the synthesis of borylsubstituted buta‐1,3‐dienes as well as their application in organic chemistry. Highly versatile: Boron‐functionalized dienes (also “linchpin” reagents) are useful class of key reagents for a variety of highly functionalized chemical transformations in the syntheses an important class of natural products showing a wide range of biological activities. This review describes progress in the synthesis of borylsubstituted buta‐1,3‐dienes as well as their application in organic chemistry.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201602124