A two-photon fluorescent turn-on probe for nitroxyl (HNO) and its bioimaging application in living tissues

The first two-photon fluorescent probe for specific detection of nitroxyl is designed and synthesized, and we have further demonstrated that the new two-photon fluorescent probe could be employed to image nitroxyl in living cells and tissues.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2015-04, Vol.51 (26), p.5754-5757
Main Authors: Zheng, Kaibo, Lin, Weiying, Cheng, Dan, Chen, Hua, Liu, Yong, Liu, Keyin
Format: Article
Language:English
Subjects:
Animals
Cell Survival
Cells (biology)
Fluorescence
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
HeLa Cells
Humans
Image detection
Liver - chemistry
Liver - cytology
Medical imaging
Molecular Imaging
Molecular Structure
Nitrogen Oxides - analysis
Photons
Rats
Synthesis
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Description
Summary:The first two-photon fluorescent probe for specific detection of nitroxyl is designed and synthesized, and we have further demonstrated that the new two-photon fluorescent probe could be employed to image nitroxyl in living cells and tissues.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc10382c