Combination of automated solid-phase and enzymatic oligosaccharide synthesis provides access to α(2,3)-sialylated glycans

A synthetic strategy combining automated solid-phase chemical synthesis and enzymatic sialylation was developed to access α(2,3)-sialylated glycans.

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2015-04, Vol.51 (28), p.6183-6185
Main Authors: Fair, Richard J, Hahm, Heung Sik, Seeberger, Peter H
Format: Article
Language:English
Subjects:
Automation
Carbohydrate Conformation
Glycan
Molecular Sequence Data
N-Acetylneuraminic Acid - chemistry
N-Acetylneuraminic Acid - metabolism
Oligosaccharides
Polysaccharides - biosynthesis
Polysaccharides - chemistry
Sialyltransferases - chemistry
Sialyltransferases - metabolism
Solid-Phase Synthesis Techniques
Strategy
Synthesis
Synthesis (chemistry)
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A synthetic strategy combining automated solid-phase chemical synthesis and enzymatic sialylation was developed to access α(2,3)-sialylated glycans.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc01368b