A highly selective long-wavelength fluorescent probe for the detection of human carboxylesterase 2 and its biomedical applications

A highly selective long-wavelength fluorescent probe TCFB has been developed for the detection of hCE2. The probe can be used for real-time monitoring of hCE2 activity in complex biological systems.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2014-01, Vol.50 (93), p.14519-14522
Main Authors: Feng, Lei, Liu, Zhao-Ming, Xu, Liang, Lv, Xia, Ning, Jing, Hou, Jie, Ge, Guang-Bo, Cui, Jing-Nan, Yang, Ling
Format: Article
Language:English
Subjects:
Biological activity
Biological monitoring
Biomedical materials
Carboxylesterase - analysis
Carboxylesterase - metabolism
Cell Line, Tumor
Enzyme Activation
Fluorescence
Fluorescent Dyes - analysis
Fluorescent Dyes - chemistry
Humans
Models, Molecular
Molecular Structure
Real time
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Description
Summary:A highly selective long-wavelength fluorescent probe TCFB has been developed for the detection of hCE2. The probe can be used for real-time monitoring of hCE2 activity in complex biological systems.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc06642a