Biosynthesis of lactic acid in a membrane bioreactor for cleaner technology of polylactide production

A low-waste and high intensive method of lactic acid microbial synthesis for polylactide production has been developed. The biosynthesis proceeds at the semicontinuous cultivation in a membrane bioreactor without removal of the biomass and formation of excess of biomass of the lactic acid producer,...

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Bibliographic Details
Published in:Clean technologies and environmental policy 2017-04, Vol.19 (3), p.869-882
Main Authors: Kuznetsov, A., Beloded, A., Derunets, A., Grosheva, V., Vakar, L., Kozlovskiy, R., Shvets, V.
Format: Article
Language:English
Subjects:
Acids
Bacteria
Batch processes
Biomass
Bioreactors
Biosynthesis
Carbohydrates
Clean technology
Cleaners
Consumption
Earth and Environmental Science
Environment
Environmental Economics
Environmental Engineering/Biotechnology
Environmental policy
Fermentation
Glucose
Growth factors
Industrial and Production Engineering
Industrial Chemistry/Chemical Engineering
Lactic acid
Membrane reactors
Membranes
Microorganisms
Original Paper
Polylactides
Productivity
Reactors
Renewable resources
Sustainable Development
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Summary:A low-waste and high intensive method of lactic acid microbial synthesis for polylactide production has been developed. The biosynthesis proceeds at the semicontinuous cultivation in a membrane bioreactor without removal of the biomass and formation of excess of biomass of the lactic acid producer, with minimization of the consumption of expensive growth factors. At the laboratory experiments during 130 cycles on biosynthesis of lactic acid from glucose in a membrane reactor, the specific productivity of biochemical reactor reached 46 g of LA per liter per hour at the yield of LA from glucose close to 100 % and concentration of LA 100–120 g/L. These results are a good base for development of the cleaner technology for production of chemicals from renewable sources through lactic acid.
ISSN:1618-954X
1618-9558
DOI:10.1007/s10098-016-1275-z