Gas-diffusion microextraction coupled with spectrophotometry for the determination of formaldehyde in cork agglomerates

• Published in: Analytical and bioanalytical chemistry 2017-04, Vol.409 (11), p.2885-2892
• Main Authors: Brandão, Pedro F., Ramos, Rui M., Valente, Inês M., Almeida, Paulo J., Carro, Antonia M., Lorenzo, Rosa A., Rodrigues, José A.
• Format: Article
• Language: English
• Subjects: Acetylacetone; Agglomerates; Agglomeration; Analytical Chemistry; Asymmetry; Biochemistry; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Cork; Cork (Materials); Extraction; Food Science; Formaldehyde; Indoor air quality; Laboratory Medicine; Methodology; Monitoring/Environmental Analysis; Reagents; Research Paper; Spectrophotometry
• ISSN: 1618-2642; 1618-2650
• DOI: 10.1007/s00216-017-0233-x

In this work, a simple methodology was developed for the extraction and determination of free formaldehyde content in cork agglomerate samples. For the first time, gas-diffusion microextraction was used for the extraction of volatile formaldehyde directly from samples, with simultaneous derivatization with acetylacetone (Hantzsch reaction). The absorbance of the coloured solution was read in a spectrophotometer at 412 nm. Different extraction parameters were studied and optimized (extraction temperature, sample mass, volume of acceptor solution, extraction time and concentration of derivatization reagent) by means of an asymmetric screening. The developed methodology proved to be a reliable tool for the determination of formaldehyde in cork agglomerates with the following suitable method features: low LOD (0.14 mg kg -1 ) and LOQ (0.47 mg kg -1 ), r 2  = 0.9994, and intraday and interday precision of 3.5 and 4.9%, respectively. The developed methodology was applied to the determination of formaldehyde in different cork agglomerate samples, and contents between 1.9 and 9.4 mg kg −1 were found. Furthermore, formaldehyde was also determined by the standard method EN 717-3 for comparison purposes; no significant differences between the results of both methods were observed. Graphical abstract Representation of the GDME system and its main components.