Outcome of Triple Antiplatelet Therapy Including Cilostazol in Elderly Patients with ST-Elevation Myocardial Infarction who Underwent Primary Percutaneous Coronary Intervention: Results from the INTERSTELLAR Registry

Objectives Compared with dual antiplatelet therapy including aspirin and clopidogrel, triple antiplatelet therapy including cilostazol has a mortality benefit in patients with ST-segment elevation myocardial infarction. However, whether the mortality benefit persists in elderly patients is not clear...

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Bibliographic Details
Published in:Drugs & aging 2017-06, Vol.34 (6), p.467-477
Main Authors: Jang, Ho-Jun, Park, Sang-Don, Park, Hyun Woo, Suh, Jon, Oh, Pyung Chun, Moon, Jeonggeun, Lee, Kyounghoon, Kang, Woong Chol, Kwon, Sung Woo, Kim, Tae-Hoon
Format: Article
Language:English
Subjects:
Aged
Angioplasty
Aspirin - administration & dosage
Aspirin - adverse effects
Aspirin - therapeutic use
Cardiovascular disease
Drug Therapy, Combination
Electrocardiography
Female
Geriatrics/Gerontology
Heart attacks
Hemorrhage - chemically induced
Hemorrhage - epidemiology
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Middle Aged
Mortality
Older people
Original Research Article
Percutaneous Coronary Intervention
Pharmacology/Toxicology
Pharmacotherapy
Platelet Aggregation Inhibitors - administration & dosage
Platelet Aggregation Inhibitors - adverse effects
Platelet Aggregation Inhibitors - therapeutic use
Registries
Retrospective Studies
ST Elevation Myocardial Infarction - blood
ST Elevation Myocardial Infarction - drug therapy
ST Elevation Myocardial Infarction - surgery
Stents
Tetrazoles - administration & dosage
Tetrazoles - adverse effects
Tetrazoles - therapeutic use
Ticlopidine - administration & dosage
Ticlopidine - adverse effects
Ticlopidine - analogs & derivatives
Ticlopidine - therapeutic use
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Summary:Objectives Compared with dual antiplatelet therapy including aspirin and clopidogrel, triple antiplatelet therapy including cilostazol has a mortality benefit in patients with ST-segment elevation myocardial infarction. However, whether the mortality benefit persists in elderly patients is not clear. Methods From 2007 to 2014, 1278 patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention were retrospectively analyzed. The patients were divided into four groups by age (
ISSN:1170-229X
1179-1969
DOI:10.1007/s40266-017-0463-9