Contemporary spinal oncology treatment paradigms and outcomes for metastatic tumors to the spine: A systematic review of breast, prostate, renal, and lung metastases

Highlights • 24 studies of management of spinal metastasis were reviewed of 3457 patients. • All studies found that primary cancer type significantly influenced survival. • Median survival time highest for primary breast and renal cancers, lowest for prostate and lung cancers. • Surgery shown to gre...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2017-07, Vol.41, p.11-23
Main Authors: Yao, Amy, Sarkiss, Christopher A, Ladner, Travis R, Jenkins, Arthur L
Format: Article
Language:English
Subjects:
Breast Neoplasms - secondary
Female
Humans
Kidney Neoplasms - secondary
Lung Neoplasms - secondary
Male
Metastases
Neuro-oncology
Neurology
Prostatic Neoplasms - secondary
Radiation
Radiosurgery
Spinal Neoplasms - mortality
Spinal Neoplasms - secondary
Spinal Neoplasms - therapy
Spine
Tumor
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Summary:Highlights • 24 studies of management of spinal metastasis were reviewed of 3457 patients. • All studies found that primary cancer type significantly influenced survival. • Median survival time highest for primary breast and renal cancers, lowest for prostate and lung cancers. • Surgery shown to greatly increase quality of life in patients able to tolerate the procedure.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2017.04.004