Primary central nervous system lymphoma as a neurosurgical problem

Primary central nervous system lymphoma (PCNSL) comprises around 3–5% of primary central nervous system (CNS) tumours and around 1% of all non-Hodgkin lymphoma (NHL). Diffuse large B-cell lymphoma (DLBCL) is the most common histological type. High effectiveness of chemo- and radiotherapy for PCNSL r...

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Bibliographic Details
Published in:Neurologia i neurochirurgia polska 2017-07, Vol.51 (4), p.319-323
Main Authors: Szczepanek, Dariusz, Wąsik-Szczepanek, Ewa, Stoma, Filip, Sokołowska, Bożena, Trojanowski, Tomasz
Format: Article
Language:English
Subjects:
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - therapeutic use
Central Nervous System Neoplasms - therapy
Glucocorticoids - therapeutic use
Humans
Injections, Intraventricular
Injections, Spinal
Lymphoma
Lymphoma - therapy
Lymphoma, Large B-Cell, Diffuse - therapy
Lymphoma, Non-Hodgkin - therapy
Nervous system
Neurosurgical Procedures
Primary central nervous system lymphoma
Radiosurgery
Stereotactic biopsy
Stereotaxic Techniques
Tumors
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Summary:Primary central nervous system lymphoma (PCNSL) comprises around 3–5% of primary central nervous system (CNS) tumours and around 1% of all non-Hodgkin lymphoma (NHL). Diffuse large B-cell lymphoma (DLBCL) is the most common histological type. High effectiveness of chemo- and radiotherapy for PCNSL regrettably does not eliminate significant risks of recurrence for CNS tumours. That results in higher interest in other treatment options, including surgical procedures. PCNSL remains in the scope of interest for many specialists and neurosurgeons seem to play a more important role.
ISSN:0028-3843
1897-4260
DOI:10.1016/j.pjnns.2017.04.004