Biopsychosocial predictors of interferon-related depression in patients with Hepatitis C

Highlights • Patients with HCV treated with IFN were assessed prospectively at 4, 8, and 24 weeks. • Patients were assessed with the HAM-D, TEMPS-A and TAS questionnaires. • Early-onset depression was predicted by preexisting depressive symptoms’ and physical comorbidities. • Persistent depression w...

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Bibliographic Details
Published in:Asian journal of psychiatry 2017-04, Vol.26, p.24-28
Main Authors: Belvederi Murri, Martino, Cecere, Angela Chiara, Masotti, Mattia, Sammito, Giorgio, la Marca, Alessandra, Torres, Giuseppe Valerio, Bonfitto, Iris, Cuozzo, Edwige, Rossi, Luca, Serviddio, Gaetano, Villani, Rosanna, Picciotto, Antonino, Bellomo, Antonello, Amore, Mario
Format: Article
Language:English
Subjects:
Adult
Aged
Alexithimia
Antiviral Agents - adverse effects
Antiviral Agents - therapeutic use
Depression
Depression - chemically induced
Depression - diagnosis
Depression - psychology
Depressive Disorder - chemically induced
Depressive Disorder - diagnosis
Depressive Disorder - psychology
Female
Hepathis C
Hepatitis C - drug therapy
Hepatitis C - psychology
Humans
Interferon-alpha - adverse effects
Interferon-alpha - therapeutic use
Internal Medicine
Interpheron-alha
Male
Middle Aged
Personality
Psychiatric Status Rating Scales
Psychiatry
Risk Factors
Severity of Illness Index
Temperament
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Summary:Highlights • Patients with HCV treated with IFN were assessed prospectively at 4, 8, and 24 weeks. • Patients were assessed with the HAM-D, TEMPS-A and TAS questionnaires. • Early-onset depression was predicted by preexisting depressive symptoms’ and physical comorbidities. • Persistent depression was predicted by depressive temperament and unknown mode of contagion.
ISSN:1876-2018
1876-2026
DOI:10.1016/j.ajp.2017.01.001