Metabolic and hormonal consequences of two different meals after a moderate intensity exercise bout in obese prepubertal children

• Published in: European journal of clinical nutrition 2013-07, Vol.67 (7), p.725-731
• Main Authors: Maffeis, C, Bonadonna, R, Maschio, M, Aiello, G, Tommasi, M, Marigliano, M, Fornari, E, Morandi, A
• Format: Article
• Language: English
• Subjects: 631/443/319; 692/699/1702/393; 692/700/1720; Appetite; Basal Metabolism; Biological and medical sciences; Blood Glucose - analysis; Carbohydrates; Child; Children; Children & youth; Clinical Nutrition; Cross-Over Studies; Diet, Carbohydrate-Restricted; Diet, Fat-Restricted; Diet, High-Fat; Dietary Carbohydrates - administration & dosage; Energy balance; Energy Intake; Epidemiology; Exercise; Feeding. Feeding behavior; Fundamental and applied biological sciences. Psychology; Glucagon; Glucagon-like peptide 1; Glucagon-Like Peptide 1 - blood; Humans; Influence; Insulin - blood; Insulin Resistance; Internal Medicine; Meals; Medical sciences; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolic rate; Metabolism; Nutrient balance; Obesity; Obesity in children; Oils & fats; original-article; Oxidation; Pediatric Obesity - metabolism; Physical fitness; Postprandial Period; Public Health; Satiety; Substrates; Triglycerides; Triglycerides - blood; Vertebrates: anatomy and physiology, studies on body, several organs or systems
• ISSN: 0954-3007; 1476-5640
• DOI: 10.1038/ejcn.2013.86

Background/objectives: To investigate the relationship between postprandial nutrient balance, satiety and hormone changes induced by two different meals taken after a moderate intensity exercise bout. Subjects/Methods: Ten prepubertal obese children participated in the study. The experiment was designed as a cross-over study for repeated measures. Each test period lasted five consecutive hours during which the children were under medical supervision. The effects of two isocaloric meals were compared after a moderate intensity exercise (4 multiples of resting metabolic rate, 30 min, cycling): a low-fat/high-carbohydrate meal (meal A) and a high-fat/low-carbohydrate meal (meal B). Pre and postprandial (3 h) substrate oxidation, biochemical parameters, gastrointestinal hormone concentrations and appetite were measured. Results: The main results were: (i) higher fat balance (5.1±5.0 vs −5.0±6.6 g, P =0.001) and lower carbohydrate balance after meal B than A (−9.7±13.3 vs 11.3±18.3 g, P