Investigation of anthropometric, biochemical and dietary parameters of obese children with and without non-alcoholic fatty liver disease

• Published in: Appetite 2012-12, Vol.59 (3), p.939-944
• Main Authors: Papandreou, Dimitrios, Karabouta, Zaharoula, Pantoleon, Athina, Rousso, Israel
• Format: Article
• Language: English
• Subjects: Adolescent; Body Mass Index; carbohydrate intake; Child; Children; Diet - adverse effects; Dietary Carbohydrates - adverse effects; Dietary Carbohydrates - metabolism; Dietary Fats - adverse effects; Dietary Fats - metabolism; Dietary Fats - therapeutic use; dietary fiber; disease outbreaks; eating habits; Fatty Acids - adverse effects; Fatty Acids - metabolism; Fatty Acids, Omega-3 - metabolism; Fatty Acids, Omega-3 - therapeutic use; fatty liver; Fatty Liver - epidemiology; Fatty Liver - etiology; Fatty Liver - metabolism; Female; girls; Greece; Humans; Insulin Resistance; lifestyle; liver; Liver - metabolism; Male; N-3 fatty acids; Non-alcoholic fatty liver disease; Obesity; Obesity - complications; Obesity - metabolism; Odds Ratio; omega-3 fatty acids; pathogenesis; Prevalence; Regression Analysis; Risk Factors; saturated fatty acids; Severity of Illness Index; ultrasonography; Waist Circumference
• ISSN: 0195-6663; 1095-8304
• DOI: 10.1016/j.appet.2012.09.006

► We investigated risk factors related of obese children with and without NAFLD. ► Dietary levels of CHO, SFA and fiber were found to be correlated with NAFLD. ► Insulin Resistance and n-3 FA was found independently associated with NAFLD. Non-alcoholic fatty liver disease (NAFLD) in children has been recognized as a major health burden. The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity, unhealthy dietary pattern, and sedentary lifestyle. The purpose of this study was to investigate anthropometric, biochemical and dietary intake parameters of obese Greek children with and without NAFLD. Eighty two obese children aged 8–15 (45 boys/37 girls) participated in the study. Ultrasonography (US) was used to diagnose NAFLD in all participated subjects. Liver indexes were measured in all children. A 3-day dietary was recorded for all subjects. Data for continuous variables is expressed as mean values±standard deviation. Thirty-five out of eighty two subjects (42.6%) had NAFLD. Body Mass Index levels (P